In addition to the body immune system, endothelial cells that line capillary likewise appeared to play a crucial function in the development of COVID toes and chilblains..
” The epidemiology and scientific features of chilblain-like sores have actually been extensively studied and released, however, little is learnt about the pathophysiology involved,” said senior author Charles Cassius, MD, of Hôpital Saint-Louis, in Paris, France. “Our research study offers brand-new insights.”.
Reference: 6 October 2021, British Journal of Dermatology.DOI: 10.1111/ bjd.20707.
By Wiley
October 5, 2021
Redness and swelling of the toes and hands, understood as chilblain-like lesions, have been reported during the COVID-19 pandemic. A new study released in the British Journal of Dermatology uncovers the hidden systems associated with such “COVID toes” signs..
The research study consisted of 50 individuals with COVID toes and 13 with comparable chilblains lesions that arose before the pandemic. The mechanisms behind both types involved an immune response with high levels of certain autoantibodies along with type I interferon, an essential protein in the antiviral action.