November 22, 2024

What Antibody Response Level Protects Against COVID-19 Death?

By Wiley
October 5, 2021

In a study of patients with COVID-19 being treated in extensive care units, people who mounted only a low antibody response versus the SARS-CoV-2 virus dealt with a higher risk of dying.
The research study, which is released in the Journal of Internal Medicine, also found that patients with strong antibody responses versus the virus had low levels of viral RNA in their blood. On the contrary, those with bad antibody actions had high viral RNA levels and disseminated viral proteins in the blood.

In a research study of patients with COVID-19 being treated in intensive care units, people who mounted just a low antibody response against the SARS-CoV-2 infection dealt with a greater danger of passing away. Credit: Journal of Internal Medicine
When seriously ill, the results might assist develop the optimum antibody levels needed for a private to conquer COVID-19. The research study likewise offered evidence of the value of antibodies versus the spike protein of SARS-CoV-2 to obstruct the infection replication. These are the antibodies that are caused by vaccination.
” Our findings support that treatment with exogenous antibodies in COVID-19 need to be personalized, booking this therapy for those patients with missing or low endogenous antibodies levels,” stated co– senior author Jesús F. Bermejo-Martin, MD, PhD, of the Instituto de Investigación Biomédica de Salamanca (IBSAL) & & CIBERES, in Spain.
Reference: 6 October 2021, Journal of Internal Medicine.DOI: 10.1111/ joim.13386.