March 29, 2024

Combinatorial Single Cell CRISPR Screens: Challenges and Applications

LIVE SymposiumMonday, December 13, 20211:00 – 4:00 PM Eastern TimeRegister NowThere is an urgent requirement for quantitative biomarkers for neurological and psychiatric disorders to examine disease threat, facilitate diagnoses, and measure drug treatment efficacy. Due to the selective permeability of the blood-brain barrier, there are only trace amounts of brain-derived proteins in the plasma and cerebrospinal fluid, which makes it challenging to establish practical biomarker screening for brain conditions. Researchers look beyond the traditional protein assays and integrate transcriptomics and practical imaging methods to change brain condition diagnostics.In this virtual symposium, an expert panel will discuss how advances in single-cell sequencing, fluid-based RNA detection, and practical imaging accelerate biomarker discovery to much better comprehend the brain in health and disease.Symposium program1:10 PM– Identifying Disease-Relevant Biomarkers for Spinal Muscular AtrophyAllison D. Ebert, PhD1:40 PM– A Lymphocyte-Microglia-Astrocyte Axis in Chronic Active Multiple SclerosisMartina Absinta, PhD2:10 PM– EEG Biomarkers of Fine-Scale Brain Connectivity Changes in Mental DisordersEtay Hay, PhD2:40 PM– Immune Biomarkers in Bipolar Disorder and Their Genetic BasisSarah Bergen, PhD3:10 – 4:00 PM – Open panel Q&A sessionSejal Davla from The Scientists Creative Services Team will be joined by the entire panel in an open concern and response session where speakers will resolve questions postured by the audience.Register NowMeet the speakersAllison D. Ebert, PhDAssociate ProfessorDepartment of Cell Biology, Neurobiology, and AnatomyDirector, Neuroscience Doctoral ProgramMedical College of Wisconsin, MilwaukeeMartina Absinta, PhDJunior FacultyVita-Salute San Raffaele UniversityMilan, ItalyEtay Hay, PhDIndependent ScientistKrembil Centre for NeuroinformaticsCentre for Addiction and Mental HealthAssistant ProfessorDepartments of Physiology and Psychiatry University of TorontoSarah Bergen, PhDAssociate ProfessorDepartment of Medical Epidemiology and BiostatisticsKarolinska Institute, Stockholm, SwedenSymposium Sponsors