December 23, 2024

High Triglycerides May Increase Risk of Second Stroke – Even With Statin Drugs

An atherothrombotic stroke is triggered by an embolisms that forms from plaques that develop up within blood vessels in the brain. A brand-new study recommends that people who have this type of stroke who also have higher levels of triglycerides, a type of fat, in their blood might have a greater danger of having another stroke or other cardiovascular issues one year later, compared to people who had a stroke but have lower triglyceride levels. The research study discovered an association even when individuals were taking statin drugs suggested to lower triglycerides and protect versus heart attack and stroke.
The research study looked at 870 individuals who had a stroke or transient ischemic attack.

” Our research study recommends that for individuals who had atherothrombotic stroke, having raised levels of triglycerides in their blood is a risk factor for having another stroke or other cardiovascular issues in the future, and we discovered that to be real even if the person is on statin treatment,” stated research study author Takao Hoshino, MD, of the Tokyo Womens Medical University in Japan. “The great news is that statin medications are simply one therapy for high triglycerides– diet plan and workout can also be effective methods to reduce the levels in your blood at little or no charge.”
The study took a look at 870 people who had a stroke or short-term ischemic attack. Their typical age was 70. Of those, 217, or 25%, had elevated triglyceride levels, specified as fasting triglycerides levels 150 milligrams per deciliter or greater.
Scientists followed up with the participants one year later to learn if there was an association in between high triglyceride levels and having another stroke, acute coronary syndrome, which is any condition triggered by an abrupt reduction of blood flow to the heart, or death due to vascular causes.
After changing for aspects like cholesterol level and statin use, scientists discovered that people who had high triglyceride levels had a 21% greater risk of death, heart or stroke condition one year, compared to 10% higher threat for those with lower levels.
When scientists looked specifically at people who had another stroke after an atherothrombotic stroke, they found that 14 out of 114 individuals with regular triglyceride levels, or 12%, had one during the study, compared to 33 out of 217 individuals, or 16%, of those with elevated levels.
For severe coronary syndrome, one out of 114 people, or 0.9%, with normal triglyceride levels developed the heart disease one year after an atherothrombotic stroke, compared to five out of 60, or 8%, of those with elevated levels.
Hoshino keeps in mind the study did not discover an association in between greater triglyceride levels and future cardiovascular issues in people who had a various type of stroke called cardioembolic stroke.
” More research study is required, however for people who have had an atherothrombotic stroke, triglyceride levels might emerge as a crucial target for avoiding future strokes and other cardiovascular issues,” Hoshino said. “Statin treatment is still a reliable treatment for people with high triglyceride levels, however our study highlights how essential it is to look at all the tools a person can use to lower their triglycerides, consisting of diet adjustments, exercise and taking omega-3 fatty acids.”
The research study does not show that reducing high triglyceride levels will prevent people with atherothrombotic strokes from having cardiovascular problems later; it only shows an association.
A constraint of the research study is that researchers thought about just the participants fasting levels of triglycerides.
Recommendation: “Prognostic Role of Hypertriglyceridemia in Patients With Stroke of Atherothrombotic Origin” 16 March 2022, Neurology.

Stroke can have many causes. An atherothrombotic stroke is triggered by a clot that forms from plaques that construct up within blood vessels in the brain. A brand-new research study recommends that individuals who have this kind of stroke who also have greater levels of triglycerides, a kind of fat, in their blood may have a greater threat of having another stroke or other cardiovascular problems one year later, compared to people who had a stroke but have lower triglyceride levels. The research is published in the March 16, 2022, online problem of Neurology, the medical journal of the American Academy of Neurology. When people were taking statin drugs suggested to lower triglycerides and safeguard against heart attack and stroke, the research study found an association even.
Elevated triglyceride levels are thought to contribute to hardening of the arteries and increased risk of cardiovascular disease, heart disease, and stroke.