What is a key research study challenge that your work addresses?One focus was to construct an independent testing platform to recognize whether the antibodies to histone post-translational modifications (PTMs) that everybody was investing millions of dollars on were fit for purpose. Antibodies are usually developed by immunizing bunnies and are released to the world as a single catalog number. We examine the efficiency of these reagents, showing that a given anti-PTM antibody is fit for the techniques that we have directly evaluated to nucleosome standards. We are open with end users about how each antibody has actually been confirmed for a specific application, using specified and totally transparent requirements that can be separately validated.How are you utilizing Fortis (Bethyl) antibodies to help resolve this challenge?Everybody understands how to make anti-PTM antibodies. EpiCypher will then launch all of the data that went into developing these reagents– essentially, we will reveal precisely what each antibody can do and will inspect every single lot with comparable stringency.
We assess the efficiency of these reagents, demonstrating that a provided anti-PTM antibody is fit for the approaches that we have actually directly checked to nucleosome requirements. We are open with end users about how each antibody has actually been validated for a specific application, using defined and fully transparent requirements that can be individually validated.How are you utilizing Fortis (Bethyl) antibodies to help address this challenge?Everybody understands how to make anti-PTM antibodies. EpiCypher will then release all of the data that went into developing these reagents– essentially, we will show precisely what each antibody can do and will inspect every single lot with equivalent stringency.