” It was surprising to us that such a huge enhancement can be displayed in the semen quality in connection with a weight reduction. And as 18 percent of Danes have weight problems, this new understanding might actually make a distinction,” states Professor Signe Torekov who headed the research study together with Professor Romain Barres at the Novo Nordisk Foundation Center for Basic Metabolic Research.
The new results might be outstanding news for fertility because a correlation between increased sperm count and faster pregnancy achievement has currently been revealed.
The study was released in the distinguished journal Human Reproduction, which is highly ranked in the area of fertility research. An overall of 56 overweight males aged 18-65 years with a BMI in between 32 and 43 participated in the study.
Sustained weight-loss is required
Signe Torekov describes that it has actually long been understood that weight problems is related to reduced semen quality. Previous studies have likewise suggested a link between weight loss and increased semen quality, however these research studies have actually had so few participants or such modest weight-loss that it has actually been tough to reason from them, she discusses.
” But now we are prepared to do just that. This is the very first long-term randomized study, where we have actually shown that semen quality in males with weight problems enhances with a sustained weight reduction,” says Signe Torekov at the Department of Biomedical Sciences.
” The guys lost an average of 16.5 kg which increased the sperm concentration by 50 percent and the sperm count by 40 percent eight weeks after the weight-loss. Throughout the 52 weeks, the trial lasted following the weight-loss, the guys preserved the enhanced semen quality. Just the guys who maintained the weight loss: after a year, these males had two times as lots of sperm cells as before their weight loss. The guys who restored weight lost the improvements in semen quality,” she describes.
Part of a larger study
The study is a sub-study of a significant publication on weight loss, which was released in the New England Journal of Medicine in May 2021. A total of 215 Danes with weight problems took part in the bigger research study. It was amongst these participants that 56 of the males likewise supplied semen samples to examine whether semen quality and weight-loss might be related.
In the trial, all individuals initially followed an eight-week routine with a low-calorie diet, leading to weight loss. Then the individuals were arbitrarily divided into 4 groups.
2 of the groups got placebo medication, while the other 2 groups received weight problems medication. Amongst the 2 placebo groups, one group needed to follow a workout program where weekly, they needed to do a minimum of 150 minutes of moderate physical training or 75 minutes of difficult training– or a combination.
The other group did not change their typical level of exercise. The two groups that received obesity medication were divided in the very same way, into a group with and a group without an exercise program.
After a year, it was shown that the group that only worked out and did not get medication, along with the group that only got obesity medication and did not exercise, maintained the weight loss of 13 kg. The group that both received obesity medication and exercised lost extra weight and improved health. The placebo group– those who thought they were provided medication but did not workout– had actually gained back half of the weight reduction with irritation of much of the threat factors associated with the development of type 2 diabetes and cardiovascular disease.
Referral: “Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized regulated trial” by Emil Andersen, Christian R Juhl, Emma T Kjøller, Julie R Lundgren, Charlotte Janus, Yasmin Dehestani, Marte Saupstad, Lars R Ingerslev, Olivia M Duun, Simon B K Jensen, Jens J Holst, Bente M Stallknecht, Sten Madsbad, Signe S Torekov and Romain Barrès, 17 May 2022, Human Reproduction.DOI: 10.1093/ humrep/deac096.
By University of Copenhagen – The Faculty of Health and Medical Sciences
June 29, 2022
” The males lost an average of 16.5 kg which increased the sperm concentration by 50 percent and the sperm count by 40 percent 8 weeks after the weight loss. Just the men who kept the weight loss: after a year, these guys had twice as many sperm cells as before their weight loss. It was among these individuals that 56 of the males likewise provided semen samples to investigate whether semen quality and weight loss might be related.
After a year, it was shown that the group that only exercised and did not receive medication, as well as the group that only got weight problems medication and did not workout, maintained the weight loss of 13 kg. The placebo group– those who thought they were offered medication however did not workout– had gained back half of the weight loss with stress of numerous of the threat aspects related to the development of type 2 diabetes and cardiovascular disease.
After 8 weeks of losing weight, patients increased sperm concentration by 50 percent and the sperm count by 40 percent. After a year, the men had twice as numerous sperm cells as prior to their weight loss.
Obese men can double their sperm count
Male all throughout the world are experiencing decreasing semen quality, which is typically referred to as a straight-out fertility crisis.
There might be some great news for some of the males who are having troubles.
Researchers from the University of Copenhagen and Hvidovre Hospital reveal in a brand-new clinical study that males who lose weight enhance their sperm quality– if they keep the weight off.