” While statins have been shown to minimize the risk of stroke from blood embolisms, there has been conflicting research on whether statin use decreases the risk or increases of a person having a first intracerebral hemorrhage,” said study author David Gaist, MD, Ph.D., of the University of Southern Denmark in Odense and a member of the American Academy of Neurology. “For our study, we looked at the lobe and non-lobe areas of the brain to see if the area was an element for statin usage and the danger of a very first intracerebral hemorrhage. We discovered that those who utilized a statin had a lower risk of this type of bleeding stroke in both locations of the brain.” Its reassuring news for people taking statins that these medications seem to reduce the danger of bleeding stroke as well as the risk of stroke from blood embolisms,” Gaist included.
For the study, researchers took a look at health records in Denmark and determined 989 individuals with a typical age of 76 who had an intracerebral hemorrhage in the lobe location of the brain. They were compared to 39,500 people who did not have this kind of stroke and were comparable in age, sex, and other elements.
They likewise looked at 1,175 individuals with an average age of 75 who had an intracerebral hemorrhage in the non-lobe parts of the brain. They were compared to 46,755 people who did not have this kind of stroke and were comparable in age, sex, and other aspects.
Scientists utilized prescription information to figure out details on statin use.
Of the overall individuals, 6.8% who had a stroke had been taking statins for 5 or more years, compared to 8.6% of those who did not have a stroke.
After changing for factors like high blood pressure, diabetes, and alcohol usage, researchers discovered that individuals presently using statins had a 17% lower danger of having a stroke in the lobe locations of the brain and a 16% lower threat of stroke in the non-lobe locations of the brain.
Longer use of statins was related to a lower danger of stroke in both locations of the brain. When using statins for more than five years, people had a 33% lower threat of having a stroke in the lobe area of the brain and a 38% lower risk of stroke in the non-lobe area of the brain.
” Its assuring news for individuals taking statins that these medications appear to reduce the threat of bleeding stroke in addition to the threat of stroke from blood clots,” Gaist included. “However, our research study was carried out in just the Danish population, which is primarily people of European origins. More research study must be carried out in other populations.”.
Reference: “Association Between Statin Use and Intracerebral Hemorrhage Location: A Nested Case-Control Registry Study” by Nils Jensen Boe, Stine Munk Hald, Mie Micheelsen Jensen, Jonas Asgaard Bojsen, Mohammad Talal Elhakim, Sandra Florisson, Alisa Saleh, Anne Clausen, Sören Möller, Frederik Severin Gråe Harbo, Ole Graumann, Jesper Hallas, Luis Alberto García Rodríguez, Rustam Al-Shahi Salman, Larry B. Goldstein and David Gaist, 7 December 2022, Neurology.DOI: 10.1212/ WNL.0000000000201664.
The research study was moneyed by the Novo Nordisk Foundation.
Statins are a class of drugs that lower cholesterol levels in the blood. They work by obstructing an enzyme in the liver that is accountable for producing cholesterol.
Current research links the cholesterol-lowering drugs to a lower risk of bleeding stroke..
According to recent research study individuals who utilize statins, a class of drugs that decrease cholesterol levels may have a decreased threat of an intracerebral hemorrhage. Intracerebral hemorrhage is a kind of stroke caused by bleeding in the brain. The research study was just recently published in the journal Neurology.
” While statins have been revealed to decrease the risk of stroke from embolism, there has been contrasting research study on whether statin use reduces the threat or increases of a person having a first intracerebral hemorrhage,” stated research study author David Gaist, MD, Ph.D., of the University of Southern Denmark in Odense and a member of the American Academy of Neurology. “For our research study, we looked at the lobe and non-lobe areas of the brain to see if the place was a factor for statin use and the threat of a first intracerebral hemorrhage. We discovered that those who used a statin had a lower threat of this kind of bleeding stroke in both locations of the brain. The threat was even lower with long-term statin use.”.
The lobe area of the brain includes many of the cerebrum, consisting of the frontal, parietal, temporal, and occipital lobes. The non-lobe location mainly includes the basal ganglia, thalamus, brainstem, and cerebellum.