December 23, 2024

Stressful Life Events Tied to Increased Risk of Stroke

Acute stroke, likewise referred to as a “brain attack,” is a medical emergency situation that takes place when the blood flow to the brain is disrupted or decreased, causing damage or death of brain cells. This can occur as an outcome of a blocked artery, a burst blood vessel, or a clot that travels to the brain.
New research study from the University of Galway, published in the Journal of the American Medical Association Network Open (JAMA Network Open), suggests that psychosocial tension might increase the threat of stroke.
The research study discovered that experiencing any demanding life occasion raises the threat of stroke by 17%, and experiencing two or more such events raises the threat by 31%.
The research was led by Dr. Catriona Reddin, at the University of Galways College of Medicine, Nursing, and Health Sciences. It looked at levels of tension in more than 26,000 individuals in Europe, Asia, North and South America, the Middle East, and Africa.

Dr. Catriona Reddin, University of Galways College of Medicine, Nursing and Health Sciences. Credit: Aengus McMahon
The research study discovered that increased tension in your home, tension at work, and current stressful life occasions (e.g. marital separation/divorce, major intra-family conflict) were related to an increased risk of ischaemic stroke (a stroke due to an embolism) and hemorrhagic stroke (a stroke due to bleeding within the brain tissue).
Those who reported serious work stress were over two times as most likely to have an ischaemic stroke, and over five times as most likely to have a hemorrhagic stroke compared to those who reported no work stress.
The increased danger was lower in individuals who reported feeling more in control.
Dr Reddin said: “Approximately 7,500 Irish people have a stroke, an estimated 30,000 individuals are residing in Ireland with impairments as an outcome of a stroke and annually about 2,000 Irish people pass away as an outcome of a stroke. In this most current INTERSTROKE research study, we took a look at self-reported stress.
” In individuals who reported serious home tension, the increase in stroke risk was lower in those who felt that what takes place in life is determined by factors within their control.
” Similarly, in people who reported severe work tension, the boost in stroke threat was lower in individuals who felt that they had control over what takes place in work, in the majority of circumstances, compared to people who felt that they had little control over their work life.”
Teacher Martin ODonnell, Professor of Neurovascular Medicine at the University of Galway and Consultant Stroke Physician at Galway University Hospitals, co-led the worldwide INTERSTROKE study in collaboration with Professor Salim Yusuf from the Population Health Research Institute at McMaster University, Canada.
Professor ODonnell said: “Stroke is the most typical cause of adult special needs worldwide. Stroke avoidance is important and the more we understand about the illness the better-equipped doctors and the public can be to alleviate the threats.
” The INTERSTROKE research study is giving us a much better understanding of the value of conventional and emerging danger aspects of stroke in ethnic groups and various areas internationally, which are needed to help avoidance. We understand that the very best ways to avoid stroke are to eat a healthy diet, workout routinely, and prevent smoking and drinking too much alcohol.
” In this latest study, we got deeper insights into how work and life-related stresses can contribute to stroke. The findings recommend that higher locus of control is associated with lower risk of stroke and may be a crucial effect modifier of the threat associated with psychosocial stress.”
Recommendation: “Association of Psychosocial Stress With Risk of Acute Stroke” by Catriona Reddin, MB, Robert Murphy, MB, Graeme J. Hankey, MD, Conor Judge, Ph.D., Denis Xavier, MD, Annika Rosengren, Ph.D., John Ferguson, Ph.D., Alberto Alvarez-Iglesias, Ph.D., Shahram Oveisgharan, MD, Helle K. Iversen, MD, DMSci, Fernando Lanas, Ph.D., Fawaz Al-Hussein, MD, Anna Członkowska, Ph.D., Aytekin Oguz, Ph.D., Clodagh McDermott, MD, Nana Pogosova, MD, German Málaga, MD, Peter Langhorne, Ph.D., Xingyu Wang, Ph.D., Mohammad Wasay, MD, Salim Yusuf, DPhil and Martin ODonnell, Ph.D., for the INTERSTROKE private investigators, 9 December 2022, JAMA Network Open.DOI: 10.1001/ jamanetworkopen.2022.44836.
INTERSTROKE study is one of the biggest worldwide studies of danger aspects for stroke. It has been examining information from 26,000 people in 27 countries given that 2007.