” Our results recommend that late morning exercise might be more effective than late night workout in regards to enhancing the metabolic process and the burning of fat, and if this is the case, they could show of value to individuals who are obese,” says Professor Juleen R. Zierath from the Department of Molecular Medicine and Surgery and the Department of Physiology and Pharmacology, Karolinska Institutet.
Enhance the health advantages of workout
Humans and mice share numerous basic physiological functions, and mice are a reputable design for human physiology and metabolic process. There are also essential differences, such as the fact that mice are nighttime.
” The ideal timing appears to be important to the bodys energy balance and to enhancing the health benefits of exercise, but more research studies are required to draw any trusted conclusions about the relevance of our findings to humans,” states Professor Zierath.
Recommendation: “Time of day figures out postexercise metabolism in mouse adipose tissue” by Logan A. Pendergrast, Leonidas S. Lundell, Amy M. Ehrlich, Stephen P. Ashcroft, Milena Schönke, Astrid L. Basse, Anna Krook, Jonas T. Treebak, Lucile Dollet and Juleen R. Zierath, 13 February 2023, Proceedings of the National Academy of Sciences.DOI: 10.1073/ pnas.2218510120.
The study was performed in close cooperation with the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) at the University of Copenhagen and was funded by the Novo Nordisk Foundation, Novo Nordisk, the Swedish Diabetes Foundation, the Swedish Research Council and Karolinska Institutet.
A brand-new research study from Karolinska Institutet in Sweden and the University of Copenhagen in Denmark reveals that mice that did exercise in an early active phase, which corresponds to morning workout in humans, increased their metabolism more than mice that did exercise at a time when they usually rest. To determine how the time of day at which exercise is done affects the burning of fat, researchers at Karolinska Institutet and the University of Copenhagen studied the adipose tissue of mice after a session of high-intensity exercise performed at two points of the everyday cycle, an early active phase and early rest stage (corresponding to a late early morning and late evening session, respectively, in human beings). The scientists studied numerous markers for fat metabolic process and analyzed which genes were active in adipose tissue after workout.
A current research study by Karolinska Institutet in Sweden and the University of Copenhagen in Denmark recommends that timing of exercise can influence fat metabolic process, based on research carried out on mice. The study discovered that mice who exercised throughout their early active phase (corresponding to morning exercise in people) had a greater boost in metabolic process than mice who worked out during their usual resting time.
Exercise at the correct time of the day appears able to increase fat metabolic process, at least in mice. A brand-new study from Karolinska Institutet in Sweden and the University of Copenhagen in Denmark reveals that mice that did exercise in an early active stage, which represents morning exercise in people, increased their metabolic process more than mice that did exercise at a time when they normally rest. The results are released in the journal Proceedings of the National Academy of Sciences (PNAS).
Exercise at various times of the day can affect the body in different ways considering that the biological procedures depend on the circadian rhythms of the cells. To establish how the time of day at which exercise is done impacts the burning of fat, scientists at Karolinska Institutet and the University of Copenhagen studied the adipose tissue of mice after a session of high-intensity exercise carried out at two points of the day-to-day cycle, an early active phase and early rest phase (representing a late morning and late evening session, respectively, in humans). The scientists studied different markers for fat metabolic process and evaluated which genes were active in fat after exercise.
Independent of food consumption
The scientists discovered that physical activity at an early active stage increased the expression of genes included in the breakdown of fat, thermogenesis (heat production), and mitochondria in the adipose tissue, showing a greater metabolic rate. These results were observed only in mice that worked out in the early active stage and were independent of food consumption.
