By Hebrew SeniorLife, Hinda and Arthur Marcus Institute for Aging Research Study
May 23, 2023
” Although there was no considerable association in between total flavonoid consumption and frailty, higher flavonols consumption (one of the subclasses of flavonoids) was associated with lower chances of establishing frailty. Specifically, higher quercetin consumption was the flavonoid that had the greatest association with frailty avoidance. All were totally free of frailty at standard and followed from ~ 12 years to examine frailty status (evaluated by the Fried Frailty Phenotype). Total flavonoids intake was not substantially associated with frailty onset. Flavonols intake (a type of flavonoid, in specific quercetin) was associated with lower chances of frailty onset.
A current research study published in the American Journal of Clinical Nutrition recommends that specific foods, such as blackberries and apples, which include flavonoids called quercetin, could be essential in preventing frailty in older grownups.
Foods rich in flavonoids like quercetin, found in blackberries and apples, might decrease the odds of frailty in older adults by 20%, according to a research study released in the American Journal of Clinical Nutrition. Regardless of no significant link between overall flavonoid intake and frailty, a higher intake of flavonols (a subclass of flavonoids), especially quercetin, was highly connected with avoiding frailty.
Consuming plant-based foods which contain dietary compounds called flavonols can lower your possibilities of establishing frailty.
Foods like apples and blackberries that contain flavonoids called quercetin might be the most important for frailty prevention.
Around 10% to 15% of older grownups experience frailty, a geriatric syndrome that causes a higher danger of falls, fractures, disability, mortality, and hospitalization. Existing dietary recommendations for frailty avoidance mostly concentrate on protein consumption. Nevertheless, there are lots of other foods that might have health advantages
” There might be some validity to the old saying, an apple a day keeps the doctor (or frailty) away,” said the authors. “Our findings suggest that for every single 10 mg greater intake of flavonols daily, the chances of frailty were minimized by 20%. Individuals can quickly take in 10 mg of flavonols intake each day because one medium-sized apple has about 10 mg of flavonols.”
” Although there was no substantial association between overall flavonoid consumption and frailty, greater flavonols intake (one of the subclasses of flavonoids) was connected with lower chances of establishing frailty. Specifically, greater quercetin intake was the flavonoid that had the greatest association with frailty prevention. This data recommends that there may be particular subclasses of flavonoids that have the most prospective as a dietary method for frailty avoidance,” stated coauthor Shivani Sahni, PhD, of Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, and the Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife; and Courtney L. Millar, PhD, of the Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, and the Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife.
The authors suggest that future research study must focus on dietary interventions of flavonols or quercetin for the treatment of frailty. Research is likewise needed in racially and ethnically diverse individuals.
The findings were released in the American Journal of Clinical Nutrition.
Referral: “Higher Intake Of Dietary Flavonols, Specifically Dietary Quercetin, Is Associated With Lower Odds Of Frailty Onset Over 12-Years Of Follow-Up Among Adults In The Framingham Heart Study” by Steven Oei, MSc, Courtney L. Millar, PhD, Thuy Nga Nguyen, RN, BSN, Kenneth J. Mukamal, MD, MPH, Douglas P. Kiel, MD, MPH, Lewis A. Lipsitz, MD, Marian T. Hannan, DSc, MPH and Shivani Sahni, PhD, 13 April 2023, American Journal of Clinical Nutrition.DOI: 10.1016/ j.ajcnut.2023.04.013.
This is among the first community-based research studies that adequately analyzed the role of dietary flavonoids for frailty avoidance.
All were complimentary of frailty at standard and followed from ~ 12 years to assess frailty status (assessed by the Fried Frailty Phenotype). Total flavonoids consumption was not considerably associated with frailty onset. Flavonols consumption (a type of flavonoid, in specific quercetin) was associated with lower odds of frailty onset.
This research study was funded by the National Institute on Aging (NIA) grant number R01 AG051728, the National Heart, Lung and Blood Institutes Framingham Heart Study (agreement numbers HHSN268201500001I and N01-HC 25195). Dr. Millar was supported by the NIA/NIH T32-AG023480 and the Beth and Richard Applebaum Research Fund. Ms. Nguyen was supported by the NIA through the Medical Student Training in Aging Research (MSTAR) Program. DPK was funded by R01 AR041398 and R01 AR061445. Dr. Lipsitz was supported by R21 AG073886 from the NIA. He also holds the Irving and Edyth S. Usen Chair in geriatric medication at Hebrew SeniorLife. Dr. Mukamal was supported by K24 AG065525.
