November 2, 2024

Depression Linked to 20% Lower Taurine Levels in Hippocampus

The typical taurine concentration in the hippocampus is 0.91 mM for the depression patient group and 1.13 mM for the healthy control group.Credit: Korea Basic Science Institute (KBSI) Pioneering Research MethodsMRI is extensively utilized in brain illness research as it can precisely scan particular areas in the body and acquire a variety of quantitative information. She included, “By using KBSIs cutting-edge research devices, we prepare to carry out follow-up research study on changes of taurine concentrations in the brain by means of long-lasting observation of depression patients, as well as the effect of taurine consumption as a treatment for depression.” Collaborative EffortThe research team at KBSI proposed the preliminary research idea of the relationship in between anxiety and taurine concentration in the hippocampus, carried out measurement of brain metabolites using 7T MRI, and carried out analysis of the resulting data.

Credit: SciTechDaily.com Precise observation using ultra-high magnetic field 7T MRI.For the first time, a research study group in Korea has actually found there is a substantial relationship in between anxiety and the taurine concentration in the hippocampus, a location of the brain responsible for memory and finding out functions. The average taurine concentration in the hippocampus is 0.91 mM for the anxiety patient group and 1.13 mM for the healthy control group.Credit: Korea Basic Science Institute (KBSI) Pioneering Research MethodsMRI is extensively utilized in brain illness research study as it can precisely scan specific places in the body and acquire a range of quantitative information. She included, “By using KBSIs cutting-edge research equipment, we prepare to conduct follow-up research study on changes of taurine concentrations in the brain through long-lasting observation of anxiety patients, as well as the impact of taurine consumption as a treatment for anxiety.” Collaborative EffortThe research group at KBSI proposed the initial research study idea of the relationship in between depression and taurine concentration in the hippocampus, carried out measurement of brain metabolites utilizing 7T MRI, and brought out analysis of the resulting information. The KIOM and CNU research groups took part in recruiting anxiety client and healthy control groups, conducted clinical interviews and mental tests, and managed market information.Reference: “Association in between taurine level in the hippocampus and major depressive disorder in young females: a proton magnetic resonance spectroscopy study at 7 Tesla” by Youngkyu Song, Jee-Hyun Cho, Hyungjun Kim, Young-Ji Eum, E-Nae Cheong, Sunyoung Choi, Jeong-Heon Park, Sungho Tak, Bumwoo Park, Jin-Hun Sohn, Gyunggoo Cho and Chaejoon Cheong, 5 September 2023, Biological Psychiatry.DOI: 10.1016/ j.biopsych.2023.08.025.