A 0.5% mass difference in between regular and ultralight enzymes (molecules with diminished heavy isotopes 13C, 2H, 15N, and 18O) needs to yield a kinetic result of no more than 1%. Second, application of the ultralight effect in biology– one can grow ultralight organisms and study their deviating residential or commercial properties. The strategies to evaluate steady isotopes in proteins, such as our Fourier Transform Isotopic Ratio Mass Spectrometry, will get enhanced interest,” Roman concludes.Reference: “Ultralight Ultrafast Enzymes” by Xuepei Zhang, Zhaowei Meng, Christian M. Beusch, Hassan Gharibi, Qing Cheng, Hezheng Lyu, Luciano Di Stefano, Jijing Wang, Amir A. Saei, Ákos Végvári, Massimiliano Gaetani and Roman A. Zubarev, 27 November 2023, Angewandte Chemie International Edition.DOI: 10.1002/ anie.202316488.
