The design was able to accurately forecast the gastrulation streams– the motion of tens of thousands of cells in the whole chick embryo– observed under a microscopic lense. Serras team “annoyed” the model– in other words, altering the initial conditions or the present parameters.A picture of the development of twin chick embryos. Credit: Mattia Serra group/ UC San DiegoThe outcomes were unexpected: the design produced cellular flows that were not observed naturally in the chick, however were observed in two other vertebrate species– the frog and fish.To make sure these outcomes were not a mathematical fantasy of the design, biology collaborators simulated the specific perturbations from the model in the laboratory on the chick embryo.
The design was able to precisely predict the gastrulation flows– the motion of tens of thousands of cells in the whole chick embryo– observed under a microscope. Serras team “troubled” the design– in other words, altering the initial conditions or the present parameters.A picture of the development of twin chick embryos. Credit: Mattia Serra group/ UC San DiegoThe results were surprising: the design created cellular circulations that were not observed naturally in the chick, however were observed in 2 other vertebrate species– the frog and fish.To make sure these results were not a mathematical fantasy of the model, biology partners imitated the exact perturbations from the model in the laboratory on the chick embryo.