Credit: SciTechDaily.comUsing a database of over 60,000 bacteria curated by researchers from across the globe, the brand-new search tool instantly matches microbes to the metabolites they produce.Researchers from the University of California San Diego, as part of a big cooperation with researchers around the world, have actually established a brand-new search tool to assist scientists much better understand the metabolism of microbes.”Reference: “microbeMASST: a taxonomically informed mass spectrometry search tool for microbial metabolomics information” by Simone Zuffa, Robin Schmid, Anelize Bauermeister, Paulo Wender P. Gomes, Andres M. Caraballo-Rodriguez, Yasin El Abiead, Allegra T. Aron, Emily C. Gentry, Jasmine Zemlin, Michael J. Meehan, Nicole E. Avalon, Robert H. Cichewicz, Ekaterina Buzun, Marvic Carrillo Terrazas, Chia-Yun Hsu, Renee Oles, Adriana Vasquez Ayala, Jiaqi Zhao, Hiutung Chu, Mirte C. M. Kuijpers, Sara L. Jackrel, Fidele Tugizimana, Lerato Pertunia Nephali, Ian A. Dubery, Ntakadzeni Edwin Madala, Eduarda Antunes Moreira, Leticia Veras Costa-Lotufo, Norberto Peporine Lopes, Paula Rezende-Teixeira, Paula C. Jimenez, Bipin Rimal, Andrew D. Patterson, Matthew F. Traxler, Rita de Cassia Pessotti, Daniel Alvarado-Villalobos, Giselle Tamayo-Castillo, Priscila Chaverri, Efrain Escudero-Leyva, Luis-Manuel Quiros-Guerrero, Alexandre Jean Bory, Juliette Joubert, Adriano Rutz, Jean-Luc Wolfender, Pierre-Marie Allard, Andreas Sichert, Sammy Pontrelli, Benjamin S. Pullman, Nuno Bandeira, William H. Gerwick, Katia Gindro, Josep Massana-Codina, Berenike C. Wagner, Karl Forchhammer, Daniel Petras, Nicole Aiosa, Neha Garg, Manuel Liebeke, Patric Bourceau, Kyo Bin Kang, Henna Gadhavi, Luiz Pedro Sorio de Carvalho, Mariana Silva dos Santos, Alicia Isabel Pérez-Lorente, Carlos Molina-Santiago, Diego Romero, Raimo Franke, Mark Brönstrup, Arturo Vera Ponce de León, Phillip Byron Pope, Sabina Leanti La Rosa, Giorgia La Barbera, Henrik M. Roager, Martin Frederik Laursen, Fabian Hammerle, Bianka Siewert, Ursula Peintner, Cuauhtemoc Licona-Cassani, Lorena Rodriguez-Orduña, Evelyn Rampler, Felina Hildebrand, Gunda Koellensperger, Harald Schoeny, Katharina Hohenwallner, Lisa Panzenboeck, Rachel Gregor, Ellis Charles ONeill, Eve Tallulah Roxborough, Jane Odoi, Nicole J. Bale, Su Ding, Jaap S. Sinninghe Damsté, Xue Li Guan, Jerry J. Cui, Kou-San Ju, Denise Brentan Silva, Fernanda Motta Ribeiro Silva, Gilvan Ferreira da Silva, Hector H. F. Koolen, Carlismari Grundmann, Jason A. Clement, Hosein Mohimani, Kirk Broders, Kerry L. McPhail, Sidnee E. Ober-Singleton, Christopher M. Rath, Daniel McDonald, Rob Knight, Mingxun Wang and Pieter C. Dorrestein, 5 February 2024, Nature Microbiology.DOI: 10.1038/ s41564-023-01575-9UC San Diego co-authors on the research study consist of: Simone Zuffa, Robin Schmid, Anelize Bauermeister, Paulo Wender P. Gomes, Andres M. Caraballo-Rodriguez, Yasin El Abiead, Jasmine Zemlin, Michael J. Meehan, Allegra T. Aron, Nicole E. Avalon, Nuno Bandeira, William H. Gerwick, Ekaterina Buzun, Marvic Carrillo Terrazas, Chia-Yun Hsu, Renee Oles, Adriana Vasquez Ayala, Jiaqi Zhao, Hiutung Chu, Mirte C. M. Kuijpers, Sara L. Jackrel, Benjamin S. Pullman, Rob Knight, and Daniel McDonald.Additional co-authors include: Alegra T. Aron at University of Denver, Emily C. Gentry at Virginia Tech, Robert H. Cichewicz at University of Oklahoma, Fidele Tugizimana, Lerato Pertunia Nephali and Ian A. Dubery at University of Johannesburg, Ntakadzeni Edwin Madala at University of Venda, Eduarda Antunes Moreira, Leticia Veras Costa-Lotufo, Norberto Peporine Lopes and Paula Rezende-Teixeira at University of São Paulo, Paula C. Jimenez at Federal University of São Paulo, Bipin Rimal, Andrew D. Patterson, Matthew F. Traxler and Rita de Cassia Pessotti at Pennsylvania State University, Daniel Alvarado-Villalobos, Giselle Tamayo-Castillo, Priscila Chaverri, Efrain Escudero-Leyva and Luis-Manuel Quiros-Guerrero, at University of Costa Rica, Alexandre Jean Bory, Juliette Joubert, Adriano Rutz, Jean-Luc Wolfender and Pierre-Marie Allard at University of Geneva, Andreas Sichert and Sammy Pontrelli at ETH Zurich, Katia Gindro and Josep Massana-Codina at Agroscope, Berenike C. Wagner, Karl Forchhammer and Daniel Petras at University of Tuebingen, Nicole Aiosa and Neha Garg. At Georgia Institute of Technology, Manuel Liebeke and Patric Bourceau at Max Planck Institute for Marine Microbiology, Kyo Bin Kang at Sookmyung Womens University, Henna Gadhavi, Luiz Pedro Sorio de Carvalho and Mariana Silva dos Santos at The Francis Crick Institute, Alicia Isabel Pérez-Lorente, Carlos Molina-Santiago and Diego Romero at Universidad de Málaga-Consejo Superior de Investigaciones Científicas Raimo Franke and Mark Brönstrup at Helmholtz Centre for Infection Research, Arturo Vera Ponce de León, Phillip Byron Pope and Sabina Leanti La Rosa, Norwegian University of Life Sciences, Giorgia La Barbera and Henrik M. Roager at University of Copenhagen, Martin Frederik Laursen, Technical University of Denmark, Fabian Hammerle, Bianka Siewert and Ursula Peintner at University of Innsbruck, Cuauhtemoc Licona-Cassani and Lorena Rodriguez-Orduña at Tecnologico de Monterrey, Evelyn Rampler, Felina Hildebrand, Gunda Koellensperger, Harald Schoeny, Katharina Hohenwallner and Lisa Panzenboeck at University of Vienna, Rachel Gregor, at Massachusetts Institute of Technology, Ellis Charles ONeill, Eve Tallulah Roxborough and Jane Odoi at University of Nottingham, Nicole J. Bale, Su Ding and Jaap S. Sinninghe Damsté at Netherlands Institute for Sea Research, Xue Li Guan at Nanyang Technological University, Jerry J. Cui and Kou-San Ju at The Ohio State University, Denise Brentan Silva and Fernanda Motta Ribeiro Silva at Federal University of Mato Grosso do Sul, Gilvan Ferreira da Silva at Embrapa Amazônia Ocidental, Hector H. F. Koolen at Universidade do Estado do Amazonas, Carlismari Grundmann at University of São Paulo, Ribeirão Preto, Jason A. Clement at Baruch S. Blumberg Institute, Hosein Mohimani at Carnegie Mellon University, Kirk Broders at the United States Department of Agriculture, Kerry L. McPhail at Oregon State University, Sidnee E. Ober-Singleton at University of Oregon, Christopher M. Rath in Emmeryville CA and Mingxun Wang at University of California, Riverside.This study was moneyed, in part, by the National Institutes of Health (grants U24DK133658, U19AG063744, 1DP2GM137413, F32AT011475, R01 GM107550, R01 GM137135, U01 DK119702, S10 OD021750, 1R01LM013115, 1R01GM132649, DP1AT010885, T32 DK007202), the National Science Foundation (grant 2152526), the U.S. Department of Agriculture, Agricultural Research Service, the National Research Foundation of Korea (grants NRF-2020R1C1C1004046, NRF-2022R1A5A2021216 and NRF-2022M3H9A2096191), the Austrian Science Fund (grant P31915), the German Research Foundation (grants EXC 2124 and TRR 261), the São Paulo Research Foundation (grants # 2018/24865 -4, # 2019/03008 -9, # 2020/06430 -0, # 2022/12654 -4, # 2015/17177 -6, # 2020/02207 -5, # 2021/10603 -0), National Council for Scientific and Technological Development (CNPq), the Research Council of Norway (grant 311913), the Novo Nordisk Foundation (grant NNF19OC0056246), the Independent Research Fund Denmark (grant 0171-00006B), ERA-Net Cofund project BlueBio (grant 311913), Fundação de Amparo à Pesquisa do Estado do Amazonas, Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul– FUNDECT (grants 71/032.390/ 2022 and 311/2022), the Betty and Gordon Moore Foundation and the Max Planck Society.
Credit: SciTechDaily.comUsing a database of over 60,000 bacteria curated by researchers from throughout the globe, the brand-new search tool immediately matches microorganisms to the metabolites they produce.Researchers from the University of California San Diego, as part of a large collaboration with researchers around the world, have developed a brand-new search tool to help researchers better comprehend the metabolism of microorganisms.”Reference: “microbeMASST: a taxonomically notified mass spectrometry search tool for microbial metabolomics data” by Simone Zuffa, Robin Schmid, Anelize Bauermeister, Paulo Wender P. Gomes, Andres M. Caraballo-Rodriguez, Yasin El Abiead, Allegra T. Aron, Emily C. Gentry, Jasmine Zemlin, Michael J. Meehan, Nicole E. Avalon, Robert H. Cichewicz, Ekaterina Buzun, Marvic Carrillo Terrazas, Chia-Yun Hsu, Renee Oles, Adriana Vasquez Ayala, Jiaqi Zhao, Hiutung Chu, Mirte C. M. Kuijpers, Sara L. Jackrel, Fidele Tugizimana, Lerato Pertunia Nephali, Ian A. Dubery, Ntakadzeni Edwin Madala, Eduarda Antunes Moreira, Leticia Veras Costa-Lotufo, Norberto Peporine Lopes, Paula Rezende-Teixeira, Paula C. Jimenez, Bipin Rimal, Andrew D. Patterson, Matthew F. Traxler, Rita de Cassia Pessotti, Daniel Alvarado-Villalobos, Giselle Tamayo-Castillo, Priscila Chaverri, Efrain Escudero-Leyva, Luis-Manuel Quiros-Guerrero, Alexandre Jean Bory, Juliette Joubert, Adriano Rutz, Jean-Luc Wolfender, Pierre-Marie Allard, Andreas Sichert, Sammy Pontrelli, Benjamin S. Pullman, Nuno Bandeira, William H. Gerwick, Katia Gindro, Josep Massana-Codina, Berenike C. Wagner, Karl Forchhammer, Daniel Petras, Nicole Aiosa, Neha Garg, Manuel Liebeke, Patric Bourceau, Kyo Bin Kang, Henna Gadhavi, Luiz Pedro Sorio de Carvalho, Mariana Silva dos Santos, Alicia Isabel Pérez-Lorente, Carlos Molina-Santiago, Diego Romero, Raimo Franke, Mark Brönstrup, Arturo Vera Ponce de León, Phillip Byron Pope, Sabina Leanti La Rosa, Giorgia La Barbera, Henrik M. Roager, Martin Frederik Laursen, Fabian Hammerle, Bianka Siewert, Ursula Peintner, Cuauhtemoc Licona-Cassani, Lorena Rodriguez-Orduña, Evelyn Rampler, Felina Hildebrand, Gunda Koellensperger, Harald Schoeny, Katharina Hohenwallner, Lisa Panzenboeck, Rachel Gregor, Ellis Charles ONeill, Eve Tallulah Roxborough, Jane Odoi, Nicole J. Bale, Su Ding, Jaap S. Sinninghe Damsté, Xue Li Guan, Jerry J. Cui, Kou-San Ju, Denise Brentan Silva, Fernanda Motta Ribeiro Silva, Gilvan Ferreira da Silva, Hector H. F. Koolen, Carlismari Grundmann, Jason A. Clement, Hosein Mohimani, Kirk Broders, Kerry L. McPhail, Sidnee E. Ober-Singleton, Christopher M. Rath, Daniel McDonald, Rob Knight, Mingxun Wang and Pieter C. Dorrestein, 5 February 2024, Nature Microbiology.DOI: 10.1038/ s41564-023-01575-9UC San Diego co-authors on the study include: Simone Zuffa, Robin Schmid, Anelize Bauermeister, Paulo Wender P. Gomes, Andres M. Caraballo-Rodriguez, Yasin El Abiead, Jasmine Zemlin, Michael J. Meehan, Allegra T. Aron, Nicole E. Avalon, Nuno Bandeira, William H. Gerwick, Ekaterina Buzun, Marvic Carrillo Terrazas, Chia-Yun Hsu, Renee Oles, Adriana Vasquez Ayala, Jiaqi Zhao, Hiutung Chu, Mirte C. M. Kuijpers, Sara L. Jackrel, Benjamin S. Pullman, Rob Knight, and Daniel McDonald.Additional co-authors consist of: Alegra T. Aron at University of Denver, Emily C. Gentry at Virginia Tech, Robert H. Cichewicz at University of Oklahoma, Fidele Tugizimana, Lerato Pertunia Nephali and Ian A. Dubery at University of Johannesburg, Ntakadzeni Edwin Madala at University of Venda, Eduarda Antunes Moreira, Leticia Veras Costa-Lotufo, Norberto Peporine Lopes and Paula Rezende-Teixeira at University of São Paulo, Paula C. Jimenez at Federal University of São Paulo, Bipin Rimal, Andrew D. Patterson, Matthew F. Traxler and Rita de Cassia Pessotti at Pennsylvania State University, Daniel Alvarado-Villalobos, Giselle Tamayo-Castillo, Priscila Chaverri, Efrain Escudero-Leyva and Luis-Manuel Quiros-Guerrero, at University of Costa Rica, Alexandre Jean Bory, Juliette Joubert, Adriano Rutz, Jean-Luc Wolfender and Pierre-Marie Allard at University of Geneva, Andreas Sichert and Sammy Pontrelli at ETH Zurich, Katia Gindro and Josep Massana-Codina at Agroscope, Berenike C. Wagner, Karl Forchhammer and Daniel Petras at University of Tuebingen, Nicole Aiosa and Neha Garg. At Georgia Institute of Technology, Manuel Liebeke and Patric Bourceau at Max Planck Institute for Marine Microbiology, Kyo Bin Kang at Sookmyung Womens University, Henna Gadhavi, Luiz Pedro Sorio de Carvalho and Mariana Silva dos Santos at The Francis Crick Institute, Alicia Isabel Pérez-Lorente, Carlos Molina-Santiago and Diego Romero at Universidad de Málaga-Consejo Superior de Investigaciones Científicas Raimo Franke and Mark Brönstrup at Helmholtz Centre for Infection Research, Arturo Vera Ponce de León, Phillip Byron Pope and Sabina Leanti La Rosa, Norwegian University of Life Sciences, Giorgia La Barbera and Henrik M. Roager at University of Copenhagen, Martin Frederik Laursen, Technical University of Denmark, Fabian Hammerle, Bianka Siewert and Ursula Peintner at University of Innsbruck, Cuauhtemoc Licona-Cassani and Lorena Rodriguez-Orduña at Tecnologico de Monterrey, Evelyn Rampler, Felina Hildebrand, Gunda Koellensperger, Harald Schoeny, Katharina Hohenwallner and Lisa Panzenboeck at University of Vienna, Rachel Gregor, at Massachusetts Institute of Technology, Ellis Charles ONeill, Eve Tallulah Roxborough and Jane Odoi at University of Nottingham, Nicole J. Bale, Su Ding and Jaap S. Sinninghe Damsté at Netherlands Institute for Sea Research, Xue Li Guan at Nanyang Technological University, Jerry J. Cui and Kou-San Ju at The Ohio State University, Denise Brentan Silva and Fernanda Motta Ribeiro Silva at Federal University of Mato Grosso do Sul, Gilvan Ferreira da Silva at Embrapa Amazônia Ocidental, Hector H. F. Koolen at Universidade do Estado do Amazonas, Carlismari Grundmann at University of São Paulo, Ribeirão Preto, Jason A. Clement at Baruch S. Blumberg Institute, Hosein Mohimani at Carnegie Mellon University, Kirk Broders at the US Department of Agriculture, Kerry L. McPhail at Oregon State University, Sidnee E. Ober-Singleton at University of Oregon, Christopher M. Rath in Emmeryville CA and Mingxun Wang at University of California, Riverside.This study was funded, in part, by the National Institutes of Health (grants U24DK133658, U19AG063744, 1DP2GM137413, F32AT011475, R01 GM107550, R01 GM137135, U01 DK119702, S10 OD021750, 1R01LM013115, 1R01GM132649, DP1AT010885, T32 DK007202), the National Science Foundation (grant 2152526), the U.S. Department of Agriculture, Agricultural Research Service, the National Research Foundation of Korea (grants NRF-2020R1C1C1004046, NRF-2022R1A5A2021216 and NRF-2022M3H9A2096191), the Austrian Science Fund (grant P31915), the German Research Foundation (grants EXC 2124 and TRR 261), the São Paulo Research Foundation (grants # 2018/24865 -4, # 2019/03008 -9, # 2020/06430 -0, # 2022/12654 -4, # 2015/17177 -6, # 2020/02207 -5, # 2021/10603 -0), National Council for Scientific and Technological Development (CNPq), the Research Council of Norway (grant 311913), the Novo Nordisk Foundation (grant NNF19OC0056246), the Independent Research Fund Denmark (grant 0171-00006B), ERA-Net Cofund project BlueBio (grant 311913), Fundação de Amparo à Pesquisa do Estado do Amazonas, Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul– FUNDECT (grants 71/032.390/ 2022 and 311/2022), the Betty and Gordon Moore Foundation and the Max Planck Society.
