Credit: DeSimone Research Group, SEM courtesy of Stanford Nano Shared FacilitiesA new procedure for microscale 3D printing creates particles of almost any shape for applications in medicine, production, research study, and more– at the speed of up to 1 million particles a day.3D-printed tiny particles, so little that to the naked eye they look like dust, have applications in drug and vaccine delivery, microelectronics, microfluidics, and abrasives for elaborate manufacturing.”We can now create much more complicated shapes down to the tiny scale, at speeds that have actually not been revealed for particle fabrication formerly, and out of a large range of products,” stated Jason Kronenfeld, PhD prospect in the DeSimone lab at Stanford and lead author of the paper that information this procedure, released today in Nature.This work constructs on a printing method known as continuous liquid user interface production, or CLIP, introduced in 2015 by DeSimone and coworkers. Prior to r2rCLIP, a batch of printed particles would need to be manually processed, a labor-intensive and sluggish process.
Credit: DeSimone Research Group, SEM courtesy of Stanford Nano Shared FacilitiesA new procedure for microscale 3D printing creates particles of nearly any shape for applications in medication, manufacturing, research study, and more– at the speed of up to 1 million particles a day.3D-printed tiny particles, so little that to the naked eye they look like dust, have applications in drug and vaccine delivery, microelectronics, microfluidics, and abrasives for intricate manufacturing.”We can now develop much more complex shapes down to the microscopic scale, at speeds that have not been shown for particle fabrication previously, and out of a large range of materials,” stated Jason Kronenfeld, PhD prospect in the DeSimone lab at Stanford and lead author of the paper that information this process, published today in Nature.This work constructs on a printing technique understood as continuous liquid interface production, or CLIP, presented in 2015 by DeSimone and coworkers.”Using light to produce items without molds opens up an entire new horizon in the particle world,” said Joseph DeSimone, the Sanjiv Sam Gambhir Professor in Translational Medicine at Stanford Medicine and corresponding author of the paper. Prior to r2rCLIP, a batch of printed particles would require to be by hand processed, a labor-intensive and slow process.”Reference: “Roll-to-roll, high-resolution 3D printing of shape-specific particles” by Jason M. Kronenfeld, Lukas Rother, Max A. Saccone, Maria T. Dulay and Joseph M. DeSimone, 13 March 2024, Nature.DOI: 10.1038/ s41586-024-07061-4Additional co-authors are Lukas Rother, who was a going to masters student at the time of this work, and Max Saccone, a postdoctoral scholar in chemical engineering and radiology.