November 2, 2024

The Future of Skin Regeneration: 3D Bioprinting From Fat Tissue

A brand-new 3D bioprinting approach using fat tissue allows the printing of layered living skin and hair roots, guaranteeing enhanced outcomes for reconstructive surgical treatment and hair development treatments. It likewise has a role in hair roots cycling, particularly in assisting in hair development.”Reference: “Intraoperative bioprinting of human adipose-derived stem cells and extra-cellular matrix induces hair follicle-like downgrowths and adipose tissue formation throughout full-thickness craniomaxillofacial skin reconstruction” by Youngnam Kang, Miji Yeo, Irem Deniz Derman, Dino J. Ravnic, Yogendra Pratap Singh, Mecit Altan Alioglu, Yang Wu, Jasson Makkar, Ryan R. Driskell and Ibrahim T. Ozbolat, 9 November 2023, Bioactive Materials.DOI: 10.1016/ j.bioactmat.2023.10.034 Ravnic and Ozbolat likewise are associated with the Huck Institutes of the Life Sciences and the Penn State Cancer Institute.

A new 3D bioprinting method using fat tissue enables the printing of layered living skin and hair roots, promising improved results for reconstructive surgical treatment and hair growth treatments. The U.S. Patent and Trademark Office gave the team a patent in February for the bioprinting innovation it used and established in this study.Advancements in Reconstructive Surgery”Reconstructive surgical treatment to fix trauma to the face or head from injury or disease is normally imperfect, resulting in scarring or permanent hair loss,” stated Ibrahim T. Ozbolat, teacher of engineering science and mechanics, of biomedical engineering and of neurosurgery at Penn State, who led the worldwide cooperation that conducted the work. “With this work, we demonstrate bioprinted, full-thickness skin with the possible to grow hair in rats. It likewise has a function in hair roots biking, particularly in helping with hair growth.”Reference: “Intraoperative bioprinting of human adipose-derived stem cells and extra-cellular matrix causes hair follicle-like downgrowths and adipose tissue formation throughout full-thickness craniomaxillofacial skin restoration” by Youngnam Kang, Miji Yeo, Irem Deniz Derman, Dino J. Ravnic, Yogendra Pratap Singh, Mecit Altan Alioglu, Yang Wu, Jasson Makkar, Ryan R. Driskell and Ibrahim T. Ozbolat, 9 November 2023, Bioactive Materials.DOI: 10.1016/ j.bioactmat.2023.10.034 Ravnic and Ozbolat also are associated with the Huck Institutes of the Life Sciences and the Penn State Cancer Institute.