This finding, part of a collaborative research study including specialists in different medical fields, uses insights into viral replication processes and prospective pathways for developing effective Ebola treatments.A U.S.-Canada study co-led by UdeM scientists offers crucial understanding of Ebola virus replication and prospective therapeutic targets.Scientists in Canada and the U.S. have found a brand-new way in which Ebola– an often lethal virus affecting individuals mainly in sub-Saharan Africa– replicates in the body.By shedding light on how the infection engages with a human protein called ubiquitin, the scientists have also recognized a prospective target for brand-new drugs to prevent the disease.Published in PLOS Biology, the study includes pharmacologists at Université de Montréal, infectious-disease specialists at Rutgers University, and microbiologists, immunologists and pathologists at the University of Texas Medical Branch (Galveston). Understanding Viral Replication” We utilized a combination of speculative and computational approaches to investigate the interaction between the Ebola virus VP35 protein and ubiquitin chains,” said co-author Rafael Najmanovich, a teacher in the pharmacology department of UdeMs medical professors. Understanding the intricate processes by which the virus reproduces within the human body is necessary for developing efficient treatments.The brand-new research study deciphers some of the molecular complexities of Ebola infection replication, shedding light on crucial proteins and pathways involved in the procedure.