December 23, 2024

A Cell-by-Cell Map of the Entire Mouse Brain

ArticleA vibrant mosaic that maps the positions and functions of cells in the mouse brain offers insights into its practical complexities.Image Credit: The Xiaowei Zhuang Laboratory, Harvard University/HHMI Hongkui Zeng, a molecular and cell biologist at the Allen Institute for Brain Science, uses effective tools to clarify the secrets of the brain. In a big collective effort, scientists profiled millions of cells to chart a cellular map of a mouse brain.1″This work determines cell types and categorizes them as a way to lay the structure to comprehend the structure and function of the brain,” stated Hongkui Zeng, a molecular and cell biologist at the Allen Institute for Brain Science.To construct this atlas, researchers combined 2 complementary transcriptomics approaches. “This details showed how many unique cell types were put together into this complex machine, such as our brain, and allowed us to predict numerous functionally crucial cell-cell interactions,” said Zhuang.The atlas is a vibrant mosaic; the colors in this image represent various cell types on the left and defined brain areas on the ideal side.

ArticleA colorful mosaic that maps the positions and functions of cells in the mouse brain uses insights into its functional complexities.Image Credit: The Xiaowei Zhuang Laboratory, Harvard University/HHMI Hongkui Zeng, a molecular and cell biologist at the Allen Institute for Brain Science, uses powerful tools to illuminate the secrets of the brain. In a big collective effort, researchers profiled millions of cells to chart a cellular map of a mouse brain.1″This work determines cell types and classifies them as a way to lay the foundation to understand the structure and function of the brain,” stated Hongkui Zeng, a molecular and cell biologist at the Allen Institute for Brain Science.To build this atlas, researchers combined two complementary transcriptomics techniques. “This info showed how many unique cell types were assembled into this complex device, such as our brain, and enabled us to predict many functionally crucial cell-cell interactions,” stated Zhuang.The atlas is a colorful mosaic; the colors in this image represent various cell types on the left and specified brain areas on the right side.