November 23, 2024

Vitamin D Deficiency Linked With Increased COVID-19 Severity and Mortality

” Our results suggest that it is recommended to keep normal levels of vitamin D. This will be beneficial to those who contract the infection,” says Dr. Amiel Dror, of the Galilee Medical Center and Azrieli Faculty of Medicine of Bar-Ilan University, who led the research study. “There is a clear agreement for vitamin D supplements on a routine basis as recommended by local health authorities as well as global health organizations.”.

In a research study published on February 3, 2022, in the journal PLOS ONE scientists from the Azrieli Faculty of Medicine of Bar-Ilan University in Safed, Israel and the Galilee Medical Center in Nahariya, Israel show a correlation between vitamin D shortage and COVID-19 intensity and mortality.
The study is amongst the first to evaluate vitamin D levels prior to infection, which helps with a more accurate assessment than throughout hospitalization, when levels might be lower secondary to the viral illness. The findings reported build on results at first published on MedRxiv..
The records of 1,176 clients admitted between April 2020 and February 2021 to the Galilee Medical Center (GMC) with favorable PCR tests were looked for vitamin D levels measured two weeks to two years prior to infection.
Patients with vitamin D shortage (less than 20 ng/mL) were 14 times most likely to have important or severe case of COVID than those with more than 40 ng/mL.
Strikingly, mortality among patients with enough vitamin D levels was 2.3%, in contrast to 25.6% in the vitamin D deficient group.
The study adjusted for age, gender, season (summer/winter), persistent illness, and discovered comparable outcomes across the board highlighting that low vitamin D level contributes considerably to disease intensity and mortality.
” Our results recommend that it is advisable to preserve normal levels of vitamin D. This will be advantageous to those who contract the infection,” says Dr. Amiel Dror, of the Galilee Medical Center and Azrieli Faculty of Medicine of Bar-Ilan University, who led the research study. “There is a clear agreement for vitamin D supplements regularly as recommended by regional health authorities along with global health companies.”.
Dr. Amir Bashkin, an Endocrinologist who participated in the present research study, includes that “This is specifically real for the COVID-19 pandemic when adequate vitamin D has actually an included advantage for the appropriate immune action to respiratory disease.”.
” This study contributes to a constantly developing body of proof recommending that a clients history of vitamin D shortage is a predictive risk factor associated with poorer COVID-19 medical disease course and mortality,” stated study co-author Prof. Michael Edelstein, of the Azrieli Faculty of Medicine of Bar-Ilan University. “It is still unclear why certain individuals suffer severe repercussions of COVID-19 infection while others do not. Our finding includes a new measurement to resolving this puzzle.”.
Reference: “Pre-infection 25-hydroxyvitamin D3 levels and association with seriousness of COVID-19 health problem” by Amiel A. Dror, Nicole Morozov, Amani Daoud, Yoav Namir, Orly Yakir, Yair Shachar, Mark Lifshitz, Ella Segal, Lior Fisher, Matti Mizrachi, Netanel Eisenbach, Doaa Rayan, Maayan Gruber, Amir Bashkin, Edward Kaykov, Masad Barhoum, Michael Edelstein and Eyal Sela, 3 February 2022, PLOS ONE.DOI: 10.1371/ journal.pone.0263069 MedRxiv.

Joint Bar-Ilan University, Galilee Medical Center study verifies that adequate vitamin D levels may positively influence the outcome of infection.
Vitamin D is frequently recognized for its function in bone health, however low levels of the supplement have been associated with a series of autoimmune, cardiovascular, and contagious illness. Early on in the pandemic health authorities started to encourage individuals to take vitamin D, as it contributes in promoting immune response and might protect versus COVID-19.