The study consisted of two Phase 1 medical trials with 96 healthy male individuals. For 28 days, the males in each trial were given either two or four oral pills containing the active drug or a placebo. The study discovered that 75% of guys who took the active drug said they would be prepared to utilize it in the future, compared with 46.4% of those taking a placebo.
Presently, male contraception is restricted to vasectomies and condoms. The researchers intend to provide more choices in the future.
The research study demonstrates that two experimental male birth control tablets successfully lower testosterone.
A new study presented at ENDO 2022, the yearly conference of the Endocrine Society in Atlanta, Georgia, suggests that two experimental male birth control pills appear to effectively lower testosterone without causing inappropriate negative effects.
These medications minimize testosterone, which lowers the number of sperm. Lowering testosterone levels typically has unpleasant side results.
” Male birth control options are presently restricted to vasectomy and condoms, and are hence very restricted as compared to female alternatives,” stated lead scientist Tamar Jacobsohn of the Contraceptive Development Program at the Eunice Kennedy Shriver National Institute of Child Health and Human Development. “Development of a reliable, reversible male contraceptive approach will enhance reproductive alternatives for males and females, have a significant influence on public health by decreasing unintentional pregnancy, and permit men to have a progressively active function in household preparation.”.
The research study consisted of 2 Phase 1 clinical trials with 96 healthy male participants. For 28 days, the males in each trial were offered either 2 or 4 oral pills including the active drug or a placebo.
The research study discovered that 75% of males who took the active drug said they would be ready to utilize it in the future, compared to 46.4% of those taking a placebo. Guy who took the four-pill day-to-day dose (400 milligrams) had lower levels of testosterone than those taking the two-pill, 200-milligram dosage. There was no considerable difference between the 2 active treatment groups in fulfillment with the drug or their determination to use it in the future or suggest it to others.
” Mens positive experiences in scientific trials and high rankings of acceptability for this male pill need to serve to thrill the public about male contraception being potentially widely offered in the coming years,” Jacobsohn stated.
Fulfilling: ENDO 2022.
The study was funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development.