November 22, 2024

Selecting the Right PARP Assay

Due to their function in DNA damage response, certain poly (ADP-ribose) polymerase (PARP) protein member of the family are promising therapeutic targets for cancer. To identify inhibitors, researchers use different in vitro assays to test for PARP enzymatic activity. Rapidly creating top quality information for inhibitor testing can be difficult, however by utilizing enhanced assay components, researchers can attain sensitive and reproducible experiments to evaluate drug specificity, efficiency, and mechanism of action.Download this ebook from BPS Bioscience to discover aboutThe basics of the PARP family and their role in cancerVarious methods to determine PARP enzymatic activityHow to optimize PARP assaysSponsored by