Scientists have established a novel technique to anticipate impending heart attacks using basic blood tests and an online tool. Led by Professor Johan Sundström, the study evaluated blood samples from over 169,000 individuals, discovering 90 molecules connected to cardiovascular disease danger. This advancement offers a special opportunity for people to assess their cardiac arrest risk and may considerably boost preventive healthcare efforts.By evaluating the outcomes of a routine blood test with an online tool, you can determine your elevated risk of experiencing a cardiovascular disease in the next six months. This tool was created by researchers at Uppsala University with the objective of enhancing people drive to adopt much healthier way of life habits.Heart attacks are the most common cause of death on the planet and are increasing globally. Many high-risk individuals are not recognized or do not take their preventive treatment. Now researchers led by Professor Johan Sundström at Uppsala University have actually found that heart attacks can be anticipated with a standard blood test. The problem, according to the scientists, is that risk elements have actually formerly been confirmed in research studies involving 5 to ten years of follow-up, where just factors that are stable over time can be identified.The Dynamic Period Before a Heart Attack”However, we understand that the time simply before a cardiac arrest is extremely vibrant. The danger of a heart attack doubles during the month after a divorce, and the threat of a fatal heart event is five times as high throughout the week after a cancer medical diagnosis,” says Sundström, who is a cardiologist and teacher of epidemiology at Uppsala University.Johan Sundström, cardiologist and teacher of public health at Uppsala University. Credit: Mikael WallerstedtTogether with other European researchers, he has proceeded from the hypothesis that numerous important biological procedures are active throughout the months before a cardiovascular disease and that these might be spotted using a basic blood test.”We wished to develop techniques that would enable the health services to determine individuals who will soon suffer their first cardiovascular disease,” Sundström says.The research group had access to blood samples from 169,053 people without previous cardiovascular disease in 6 European accomplices. Within 6 months, 420 of these individuals suffered their very first cardiovascular disease. Their blood was then compared with blood from 1,598 healthy members of the mates.”We identified around 90 molecules that were connected to a risk of a first cardiac arrest. Nevertheless, the samples that are currently taken in health care now suffice to forecast the threat. We hope that this will increase individualss inspiration to take their preventive medicine or stop smoking cigarettes, for instance,” states Sundström.A Simple Online Tool for Risk AssessmentThe researchers have also established a simple online tool in which anybody can discover out their danger of having a cardiovascular disease within 6 months.”This was one of the goals of the entire study, considering that we understand that individuals feel reasonably low motivation to follow preventive treatments. If you discover that you take place to have actually an increased threat of suffering a cardiovascular disease soon, possibly you will feel more motivated to prevent it,” Sundström says.The researchers will now study the 90 or so new molecules to understand them better and see whether there are any possibilities of treatment.”We hope to be able to bring out a brand-new study here in Uppsala to see whether the online tool provides the sort of inspiration we intend,” Sundström concludes.Reference: “Markers of imminent myocardial infarction” by Stefan Gustafsson, Erik Lampa, Karin Jensevik Eriksson, Adam S. Butterworth, Sölve Elmståhl, Gunnar Engström, Kristian Hveem, Mattias Johansson, Arnulf Langhammer, Lars Lind, Kristi Läll, Giovanna Masala, Andres Metspalu, Conchi Moreno-Iribas, Peter M. Nilsson, Markus Perola, Birgit Simell, Hemmo Sipsma, Bjørn Olav Åsvold, Erik Ingelsson, Ulf Hammar, Andrea Ganna, Bodil Svennblad, Tove Fall and Johan Sundström, 12 February 2024, Nature Cardiovascular Research.DOI: 10.1038/ s44161-024-00422-2The study was funded by Hjärt-Lungfonden, Vetenskapsrådet, AFA Försäkring, and Anders Wiklöf.One of the 6 friends is from the Uppsala-based population research study EpiHealth.
The problem, according to the researchers, is that risk factors have actually previously been confirmed in studies including five to ten years of follow-up, where only aspects that are stable over time can be identified.The Dynamic Period Before a Heart Attack”However, we understand that the time simply before a heart attack is really dynamic. The danger of a heart attack doubles during the month after a divorce, and the threat of a fatal heart occasion is 5 times as high throughout the week after a cancer diagnosis,” states Sundström, who is a cardiologist and professor of public health at Uppsala University.Johan Sundström, cardiologist and professor of epidemiology at Uppsala University. We hope that this will increase individualss inspiration to take their preventive medicine or stop smoking, for example,” states Sundström.A Simple Online Tool for Risk AssessmentThe scientists have actually also developed a simple online tool in which anybody can find out their risk of having a heart attack within six months.