The relative number of different types of cells also alters according to nutrient status.The questions of how the nutrition status of the gut controls stem cell department and distinction, and how the nutrient adjustment of stem cells changes as during aging have not been comprehensively responded to. The size of the stem cells, in turn, manages the cell type into which the stem cells separate. In the past, intermittent fasting has been shown to lengthen the life-span of animals, and the results now obtained indicate that the improved preservation of stem cell function might underlie this prolongation.According to the scientists, the systems associated with the functioning, nutrient adaptation, and aging of human and fruit fly stem cells are relatively comparable. Our work on the nutrient adaptation of stem cells continues,” says Professor Ville Hietakangas from the Faculty of Biological and Environmental Sciences and the Institute of Biotechnology, University of Helsinki.Reference: “Stem cell mTOR signaling directs region-specific cell fate choices during digestive nutrient adaptation” by Jaakko Mattila, Arto Viitanen, Gaia Fabris, Tetiana Strutynska, Jerome Korzelius and Ville Hietakangas, 9 February 2024, Science Advances.DOI: 10.1126/ sciadv.adi2671.
The relative number of different types of cells also changes according to nutrient status.The concerns of how the nutrition status of the gut manages stem cell division and differentiation, and how the nutrient adjustment of stem cells changes as during aging have not been thoroughly addressed. The size of the stem cells, in turn, controls the cell type into which the stem cells distinguish. Our work on the nutrient adaptation of stem cells continues,” says Professor Ville Hietakangas from the Faculty of Biological and Environmental Sciences and the Institute of Biotechnology, University of Helsinki.Reference: “Stem cell mTOR signaling directs region-specific cell fate decisions throughout intestinal tract nutrient adjustment” by Jaakko Mattila, Arto Viitanen, Gaia Fabris, Tetiana Strutynska, Jerome Korzelius and Ville Hietakangas, 9 February 2024, Science Advances.DOI: 10.1126/ sciadv.adi2671.
