Credit: SciTechDaily.comA brand-new pilot study indicates that high-intensity exercise can cause brain-protective impacts that have the potential to not just slow down, but possibly reverse, the neurodegeneration associated with Parkinsons disease.Prior research has actually revealed that lots of forms of workout are connected to improved symptoms of Parkinsons illness. Now, a little proof-of-concept research study including 10 clients revealed that high-intensity aerobic workout maintained dopamine-producing neurons, the brain cells that are most vulnerable to damage in clients with the disease.In truth, after six months of workout, the neurons actually had grown healthier and produced stronger dopamine signals.” This is the first time imaging has actually been used to verify that the biology of the brain in those suffering with Parkinsons disease is altered by intense workout,” states Evan D. Morris, Ph.D., teacher of radiology and biomedical imaging at Yale School of Medicine and co-principal investigator of the paper.What causes Parkinsons disease?Parkinsons illness is a neurodegenerative condition caused by the misfolding of alpha-synuclein protein that is naturally present in our cells. The team hopes that its work will inspire other researchers to prioritize research study into workout and its disease-modifying potential.Parkinsons illness is the fastest-growing neurological illness.” Reference: “Intense workout increases dopamine transporter and neuromelanin concentrations in the substantia nigra in Parkinsons illness” by Bart de Laat, Jocelyn Hoye, Gelsina Stanley, Michelle Hespeler, Jennifer Ligi, Varsha Mohan, Dustin W. Wooten, Xiaomeng Zhang, Thanh D. Nguyen, Jose Key, Giulia Colonna, Yiyun Huang, Nabeel Nabulsi, Amar Patel, David Matuskey, Evan D. Morris and Sule Tinaz, 9 February 2024, npj Parkinsons Disease.DOI: 10.1038/ s41531-024-00641-1.
Credit: SciTechDaily.comA brand-new pilot research study indicates that high-intensity workout can induce brain-protective impacts that have the potential to not simply slow down, however perhaps reverse, the neurodegeneration associated with Parkinsons disease.Prior research has shown that many kinds of exercise are linked to enhanced signs of Parkinsons disease. Now, a little proof-of-concept study including 10 clients showed that high-intensity aerobic exercise maintained dopamine-producing neurons, the brain cells that are most vulnerable to destruction in clients with the disease.In fact, after 6 months of workout, the neurons in fact had actually grown healthier and produced stronger dopamine signals.” This is the first time imaging has been used to validate that the biology of the brain in those suffering with Parkinsons disease is altered by intense exercise,” states Evan D. Morris, Ph.D., professor of radiology and biomedical imaging at Yale School of Medicine and co-principal detective of the paper.What causes Parkinsons disease?Parkinsons illness is a neurodegenerative condition triggered by the misfolding of alpha-synuclein protein that is naturally present in our cells.
