Aging may be more associated to gene length than the specific functions of genes, with reduced expression of long genes across species marking a crucial aspect in aging and associated diseases. These changes are thought to stem from DNA damage resulting from cumulative exposure to harmful agents such as UV radiation or reactive oxygen types generated by our own metabolism.While a lot of research study in aging has focused on specific genes that might speed up or slow aging, investigations of exactly which genes are more susceptible to aging have actually revealed no clear pattern in terms of gene function.”For a long time, the aging field has actually been focused on genes associated with aging, but our description is that it is much more random– its a physical phenomenon related to the length of the genes and not to the specific genes included or the function of those genes,” states co-author Ander Izeta of the Biogipuzkoa Health Research Institute and Donostia University Hospital, Spain.It basically comes down to possibility; long genes simply have more potential sites that could be damaged.
Aging might be more related to gene length than the specific functions of genes, with reduced expression of long genes across types marking a key factor in aging and associated illness. These changes are thought to stem from DNA damage resulting from cumulative exposure to damaging agents such as UV radiation or reactive oxygen species created by our own metabolism.While a lot of research in aging has focused on specific genes that may speed up or slow aging, examinations of exactly which genes are more prone to aging have actually revealed no clear pattern in terms of gene function.”For a long time, the aging field has actually been focused on genes associated with aging, however our description is that it is much more random– its a physical phenomenon related to the length of the genes and not to the specific genes included or the function of those genes,” says co-author Ander Izeta of the Biogipuzkoa Health Research Institute and Donostia University Hospital, Spain.It basically comes down to chance; long genes just have more possible sites that might be damaged.