“Our study demonstrates that d-limonene can regulate the effects of THC in a significant way and make THC more tolerable to people using it for both non-therapeutic and restorative purposes.”Methodology and FindingsIn the research study, 20 healthy adults with a typical age of 26 participated in up to 10 outpatient sessions, throughout which they inhaled vaporized d-limonene alone, vaporized THC alone, vaporized THC and d-limonene together, or vaporized distilled water (as a placebo). They likewise gathered blood and urine samples from each topic before, throughout, and after each six-hour session to test for THC and d-limonene levels.The research study team concluded that combining d-limonene with THC significantly lowered subjective indicators/reports of THC-induced stress and anxiety in individuals.”This study is a first step in revealing how we can mitigate threats of THC when used in medication, and likewise is targeted at making marijuana safer for the basic, non-therapeutic customer,” states study lead author Tory Spindle, Ph.D., associate teacher of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine.The scientists plan to continue experimenting with other terpenes alone and in combination with THC to see how they interact with each other, as well as replicate the d-limonene study in larger and more varied medical populations.
“Methodology and FindingsIn the research study, 20 healthy adults with a typical age of 26 participated in up to 10 outpatient sessions, during which they breathed in vaporized d-limonene alone, vaporized THC alone, vaporized THC and d-limonene together, or vaporized distilled water (as a placebo). They also collected blood and urine samples from each subject before, throughout, and after each six-hour session to test for THC and d-limonene levels.The research team concluded that integrating d-limonene with THC significantly reduced subjective indicators/reports of THC-induced stress and anxiety in participants.”This research study is a first action in discovering how we can mitigate dangers of THC when used in medicine, and also is targeted at making cannabis more secure for the general, non-therapeutic customer,” states research study lead author Tory Spindle, Ph.D., associate teacher of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine.The researchers plan to continue experimenting with other terpenes alone and in mix with THC to see how they communicate with each other, as well as replicate the d-limonene research study in larger and more varied clinical populations.