May 6, 2024

COVID-19 Treatment Remdesivir Dominated Hospital Drug Spending in 2021

” Drug expenditures played a substantial role in the rise in healthcare expenses stimulated by the COVID-19 pandemic,” stated Daniel J. Cobaugh, Pharm.D., FAACT, DABAT, vice president of publishing at ASHP and editor-in-chief of AJHP. “Our annual report provides the vital context required for healthcare facility and health-system leaders, policymakers, and others to understand the intricate factors influencing drug expenditure patterns and prepare for future growth and costs.”
Overall drug costs in the U.S. grew 7.7% in 2021 to $576.9 billion. Higher usage and brand-new drugs drove spending development, even though drug rates decreased by up to 1.4%.
” The drug spending whiplash that hospitals and clinics experienced in the very first year of the pandemic did not end with 2021,” said the reports lead author, Eric Tichy, Pharm.D., M.B.A., department chair, supply chain management at Mayo Clinic, Rochester, Minnesota. “Uncertainty remains around how long the federal government will continue to pay for COVID treatments, and around inflation, which is moving through a lot of financial sectors.”
A moderating factor on drug costs was the increased use of biosimilars, the generic versions of biological medications. “In oncology, were utilizing more biosimilars than we are the begetter drugs.
New drugs also contributed in investing development. Aducanumab, approved in 2021 for Alzheimers illness, was anticipated to be a big expense for health centers and centers due to its high expense and a possibly big population. However costs on the drug was less than $2 million, with the suddenly low use credited to concerns about information supporting its use, high expense, lack of clarity about compensation, and complex monitoring requirements.
In 2022, generics will likely have an impact on spending as several major top quality drugs are anticipated to lose patent defense. This includes vasopressin, an antidiuretic in usage for more than a century that was nonetheless provided patent defense under the Unapproved Drugs Initiative, making it the fifth-highest drug expense in hospitals.
New drug approvals are likewise expected in oncology, the top spending category in the report. Tichy thinks the Food and Drug Administration will approve 5 new immune-checkpoint inhibitors, which treat a range of cancers and represent approximately a third of oncology drug expenditures.
” After this year we anticipate there to be 12 immune-checkpoint inhibitors on the marketplace,” Tichy said. “They all work similarly, however we have not actually seen rate competitors between them. With more immune-checkpoint inhibitors on the market, were enthusiastic competition may drive down rates.”
The report is released online ahead of print and will appear in print in the July 15 edition of AJHP.
Recommendation:” National patterns in prescription drug expenses and projections for 2022 Get access Arrow” by Eric M Tichy, PharmD, MBA, BCPS, FCCP, FAST, James M Hoffman, PharmD, MS, Katie J Suda, PharmD, MS, Matthew H Rim, PharmD, MS, Mina Tadrous, PharmD, MS, PhD, Sandra Cuellar, PharmD, BCOP, John S Clark, PharmD, MS, BCPS, FASHP, Jennifer Ward, MBA, Glen T Schumock, PharmD, MBA, PhD, FCCP, 6 April 2022, American Journal of Health-System Pharmacy.DOI: 10.1093/ ajhp/zxac102.
ASHP (American Society of Health-System Pharmacists) is the cumulative voice of pharmacists who work as patient care companies in health centers, health systems, ambulatory clinics, and other health care settings spanning the complete spectrum of medication usage. The companys more than 60,000 members consist of pharmacists, trainee pharmacists, and drug store professionals. For 80 years, ASHP has been at the forefront of efforts to improve medication use and improve client security.

Overall drug costs in the U.S. grew 7.7% in 2021 to $576.9 billion. Higher utilization and new drugs drove spending development, even though drug costs decreased by up to 1.4%. A moderating aspect on drug costs was the increased usage of biosimilars, the generic versions of biological medications. New drugs likewise played a function in investing growth. Spending on the drug was less than $2 million, with the suddenly low use attributed to issues about data supporting its use, high expense, lack of clarity about compensation, and intricate monitoring requirements.

Clinic and healthcare facility drug costs increased due to higher use and new drugs; rate increases remained below inflation.
The COVID-19 treatment remdesivir dominated healthcare facility drug costs in 2021, accounting for nearly 10% of all pharmaceutical expenses and exceeding the next three drugs combined, according to the ASHP (American Society of Health-System Pharmacists) National Trends in Prescription Drug Expenditures and Projections for 2022.