May 11, 2024

Use of Psychedelic Drug Psilocybin (Magic Mushrooms) Associated With Lower Risk of Opioid Addiction

By Scientific Reports
April 8, 2022

Psilocybin mushrooms
Adults who have at a long time in their life utilized psilocybin– a psychedelic compound produced by some types of mushrooms– are 30% less most likely to have opioid use condition, according to a nationally representative study of United States grownups reported in the journal Scientific Reports.

The researchers found that opioid usage disorder was 30% less likely amongst those had used psilocybin, compared to those who had never used it. Those who used psilocybin were also in between 17% and 34% less likely to have experienced 7 of the 11 symptoms of opioid dependence and abuse in the previous year, compared to those who had never ever utilized it.
The authors hypothesize that psilocybin may protect against opioid usage disorder by impacting the transmission of serotonin and dopamine– neurotransmitters that previous research study has discovered are associated with dependency. Additionally, they suggest that the spiritual or magical experiences that psilocybin induces might reduce the possibility of users establishing opioid usage disorder as previous research studies have actually observed associations in between spiritual experiences and beliefs and favorable compound abuse recovery results. Additional research study, consisting of long-lasting medical trials and observational research studies, is needed to investigate the relationship between psilocybin and opioid use, they include.
Reference: “Associations in between classic psychedelics and opioid use disorder in a nationally-representative U.S. adult sample” by Grant Jones, Jocelyn A. Ricard, Joshua Lipson and Matthew K. Nock, 7 April 2022, Scientific Reports.DOI: 10.1038/ s41598-022-08085-4.

Grant Jones and coworkers investigated the incidence of opioid use condition and the prevalence of psychedelic use amongst 214,505 adults utilizing survey information gathered between 2015 and 2019. The scientists discovered that opioid usage condition was 30% less likely amongst those had used psilocybin, compared to those who had never ever utilized it. Those who utilized psilocybin were also between 17% and 34% less most likely to have experienced seven of the 11 symptoms of opioid reliance and abuse in the previous year, compared to those who had never used it.

Psilocybin mushrooms; commonly called magic mushrooms or shrooms, are a group of fungis that contain psilocybin which turns into psilocin upon ingestion. Psilocybin is a naturally happening psychedelic prodrug compound, which means it is a biologically non-active substance that the body transforms into a drug.

Grant Jones and associates examined the occurrence of opioid use condition and the frequency of psychedelic use among 214,505 grownups using survey data gathered in between 2015 and 2019. 22,276 (10.4%) individuals reported having actually used psilocybin and 10,284 (46%) of those also reported using heroin or prescription pain relievers recreationally at least once in their lives.