One of the most interesting findings was a practically 20% increase in levels of the antioxidant enzyme superoxide dismutase (SOD) in the taurine group, compared to a 3.5% drop in the control group. The Freitas group has been studying taurines antioxidant and anti-inflammatory residential or commercial properties for at least 10 years, initially in high-performance athletes and later on in overweight individuals, with daily does varying from 3 g to 6 g. “The results showed that oxidative tension in these people might be controlled when their diet plan was supplemented with this amino acid. The initial strategy was to look at the effects of taurine supplements in conjunction with exercise training, as well as both treatments separately. In the next research study, the group plan to include obese ladies aged 60-75 with sarcopenia, a gradual loss of muscle mass that can be exacerbated by persistent inflammation. Well offer physical training associated with taurine supplementation at 3 g per day and observe the possible alterations due to these interventions,” Freitas stated.
Oxidative stress markers were evaluated in blood samples taken previously and after the intervention. One of the most intriguing findings was a nearly 20% rise in levels of the antioxidant enzyme superoxide dismutase (SOD) in the taurine group, compared to a 3.5% drop in the control group. SOD, the scientists discuss, safeguards cells from the hazardous reactions of the superoxide radical.
” Preventing the accumulation of complimentary radicals that naturally accompanies aging most likely prevents cardiovascular disease, diabetes, and hypertension, amongst other chronic conditions,” stated Ellen de Freitas. Freitas is a teacher at the Ribeirão Preto School of Physical Education and Sports (EEFERP-USP) and co-principal private investigator for a task supported by FAPESP.
According to Freitas, really few studies of the impacts of taurine in the context of aging can be found in the clinical literature. “This research study was an initial step, targeted at investigating the perfect dosage and possible adverse effects, none of which was observed in any of the participants,” she said.
Anti-aging therapy.
Taurine is a nutrient found in particular foods, such as fish, shellfish, turkey, beef, and chicken. In addition, it is naturally produced in some tissues of the human body, particularly the liver, and is essential to the performance of the main nervous system, fertility, resistance, and eyesight.
The Freitas group has actually been studying taurines anti-oxidant and anti-inflammatory residential or commercial properties for a minimum of 10 years, at first in high-performance professional athletes and later in obese individuals, with everyday does varying from 3 g to 6 g. “The results showed that oxidative tension in these individuals might be controlled when their diet was supplemented with this amino acid. We then decided to check the technique in the context of aging. This was really novel, so we began with a really low security dosage,” Freitas said.
The preliminary strategy was to take a look at the impacts of taurine supplementation in combination with workout training, in addition to both treatments individually. Exercise is believed to be one of the main methods to control levels of oxidizing substances and antioxidants in the body, and the proper amount is believed to improve the advantages of taurine. However, because of the pandemic and the truth that the volunteers remained in a high-risk group for COVID-19 issues, the scientists selected to entirely proceed with the dietary component of the research study, which could be kept track of from another location.
2 other markers of oxidative stress were evaluated besides SOD: the antioxidant enzyme glutathione reductase (GR), which decreased substantially in both groups, and malondialdehyde (MDA), which increased 23% in the control group and reduced 4% in the taurine supplementation group.
” These outcomes were modest, but we believe a higher dose of taurine could produce more powerful proof for its benefits,” Freitas stated.
For Gabriela Abud, the first author of the short article and presently a Ph.D. candidate at the Ribeirão Preto Medical School (FMRP-USP), changes in the volunteers diet in the early months of the pandemic owing to lockdown may have impacted the results of the biochemical analysis.
” In addition to markers of oxidative tension, we analyzed levels of minerals such as selenium, magnesium, zinc, and calcium, which are important to the performance of these enzymes,” Abud described.
For Freitas, taurine supplementation is just the “cherry on the cake” and can not work wonders by itself. “A healthy lifestyle with a balanced diet plan and regular workout is basic for the anti-aging effect to occur,” she said.
In the next research study, the group strategy to consist of overweight women aged 60-75 with sarcopenia, a progressive loss of muscle mass that can be intensified by persistent swelling. “These people face an intense danger of establishing complications. Well offer physical training connected with taurine supplements at 3 g daily and observe the possible alterations due to these interventions,” Freitas stated.
It is very important to keep in mind that the benefits and risks of dietary taurine supplementation are still being investigated. Food supplements must not be taken without medical guidance.
Recommendation: “Taurine as a possible antiaging treatment: A regulated clinical trial on taurine antioxidant activity in women ages 55 to 70” by Gabriela Ferreira Abud M.Sc., Flavia Giolo De Carvalho Ph.D., Gabriela Batitucci Ph.D., Sofia Germano Travieso B.Sc., Carlos Roberto Bueno Junior Ph.D., Fernando Barbosa Junior Ph.D., Julio Sergio Marchini Ph.D. and Ellen Cristinide Freitas Ph.D., 11 June 2022, Nutrition.DOI: 10.1016/ j.nut.2022.111706.
According to a clinical trial involving 55 to 70-year-old females, adding this nutrient to the diet plan can enhance the bodys antioxidant defenses and potentially lower the opportunity of developing diabetes, hypertension, and heart disease. More research study is required to confirm its effect..
According to the study, the amino acid taurine could be utilized in anti-aging treatments.
Our cells produce potentially poisonous spin-offs called “totally free radicals” when they break down the oxygen we breathe and the food we take in each day in order to exist. Some of these particles bring out important biological functions, however if there are too many of them, the internal cell structures can be damaged, impairing the cells capability to operate and possibly leading to persistent disease. We describe this process as oxidative tension.
Our bodies have an exceptional toolbox of antioxidant enzymes that assist in preserving a healthy balance of reactive oxygen types, however as we age, these control systems decline. A recent research study released in the journal Nutrition recommends that supplementing ones diet with the amino acid taurine might be a sensible method to deal with the problem.
The study reported in the study was brought out at the University of São Paulo (USP) in Brazil. It involved 24 female volunteers aged 55 to 70. Neither the volunteers nor the researchers were aware of which group each participant belonged to.