May 6, 2024

Cell Culture Conquests: Finding and Defeating the Invisible Enemy

Scientists use different methods to secure versus impurities, consisting of using aseptic methods, adding antimicrobial agents to cell cultures, filtering reagents, and routinely screening cultures. Despite finest efforts, cell cultures become contaminated, impacting cell viability and a range of other biochemical and biomolecular pathways. When this occurs, researchers should frequently dispose of the cells and begin once again, wasting precious resources and time.Mycoplasma– a sub-micron sized germs without a cell wall– is a particularly formidable enemy because it is prevalent, resistant to commonly-used antibiotics, small enough to pass through filters, and infamously challenging to identify in cell culture. MilliporeSigmas total suite of mycoplasma detection and removal reagents, kits, and methods offer a robust, end-to-end service for finding and removing mycoplasma cell culture contamination.

Scientists use various approaches to secure versus impurities, consisting of utilizing aseptic strategies, including antimicrobial agents to cell cultures, filtering reagents, and regularly screening cultures. In spite of best efforts, cell cultures become contaminated, affecting cell practicality and a variety of other biochemical and biomolecular pathways. When this takes place, researchers need to typically dispose of the cells and begin anew, squandering valuable resources and time.Mycoplasma– a sub-micron sized germs without a cell wall– is an especially powerful enemy because it is pervasive, resistant to commonly-used prescription antibiotics, small enough to pass through filters, and infamously hard to identify in cell culture.