April 30, 2024

Vitamin D Supplements Linked to Decreased Diabetes Risk for Adults With Prediabetes

A recent evaluation released in Annals of Internal Medicine on February 7, 2023, found that higher vitamin D intake was connected to a 15% reduction in the probability of developing type 2 diabetes in adults with prediabetes.
Vitamin D supplements may lower diabetes risk for the more than 10 million adults with prediabetes.
A review of scientific trials has found that higher vitamin D intake was related to a 15 percent reduced probability for developing type 2 diabetes in grownups with prediabetes. The review was published on February 7, 2023, in Annals of Internal Medicine.
Vitamin D is a fat-soluble vitamin readily available in or included to some foods, as a supplement, or produced by the body when ultraviolet rays from sunshine strike the skin. Vitamin D has numerous functions in the body, consisting of a function in insulin secretion and glucose metabolic process. Observational studies have found an association in between having a low level of vitamin D in the blood and high danger for establishing diabetes.

Vitamin D is a fat-soluble vitamin offered in or included to some foods, as a supplement, or produced by the body when ultraviolet rays from sunlight strike the skin. The authors found that over a three-year follow-up duration, new-onset diabetes took place in 22.7 percent of grownups who received vitamin D and 25 percent of those who got placebo, which is a 15 percent relative decrease in threat. They argue that professional societies promoting vitamin D therapy have a commitment to warn physicians about both needed vitamin D intake and safe limitations.

Researchers from Tufts Medical Center performed an organized review and meta-analysis of 3 clinical trials comparing vitamin D supplement influence on diabetes danger. The authors found that over a three-year follow-up duration, new-onset diabetes happened in 22.7 percent of adults who received vitamin D and 25 percent of those who got placebo, which is a 15 percent relative reduction in risk. According to the authors, extrapolating their findings to the more than 374 million adults worldwide who have prediabetes suggests that affordable vitamin D supplementation might postpone the development of diabetes in more than 10 million people.
In an accompanying editorial, authors from University College Dublin and Food Safety Authority of Ireland, highlight that previous data have demonstrated substantial negative impacts for high vitamin D intake. They argue that professional societies promoting vitamin D therapy have a responsibility to alert physicians about both needed vitamin D consumption and safe limits. They recommend that this very-high-dose vitamin D treatment may prevent type 2 diabetes in some clients but might also trigger harm.
References:
” Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes: A Systematic Review and Meta-analysis of Individual Participant Data From 3 Randomized Clinical Trials” by Anastassios G. Pittas, MD, MS, Tetsuya Kawahara, MD, PhD, Rolf Jorde, MD, PhD, Bess Dawson-Hughes, MD, Ellen M. Vickery, MS, Edith Angellotti, MD, Jason Nelson, MPH, Thomas A. Trikalinos, MD and Ethan M. Balk, MD, MPH, 7 February 2023, Annals of Internal Medicine.DOI: 10.7326/ M22-3018.
” Preventing Type 2 Diabetes With Vitamin D: Therapy Versus Supplementation” by Malachi J. McKenna, MD and Mary A.T. Flynn, PhD, RD, 7 February 2023, Annals of Internal Medicine.DOI: 10.7326/ M23-0220.