May 3, 2024

Fast-Acting Nonhormonal Male Birth Control Prevents Pregnancy in Mice

” It is really encouraging that for the first time, there is a drug that can prevent sperm function without impacting the production,” says Celia Santi, a sperm physiologist at Washington University School of Medicine in St. Louis–” and that can be used short-term, on-demand without any visible side effects. Such a drug, which the authors call an “on-demand” birth control, hasnt been developed.Other male birth control drugs in advancement objective to limit the production of sperm but just end up being efficient after several months of taking the drugs, and it takes another 8 to 12-week modification duration prior to the individual taking them ends up being fertile once again. To make sure it would work as a drug, the scientists partnered with drug business TDI Therapeutics. A working male birth control drug needs to be potent and “sticky” sufficient to stick on to the right binding website even after getting in the female reproductive system, where the drugs concentration ends up being considerably watered down. The researchers also tried administering the drug orally and discovered the same decrease in the flagellar beat frequency in the animals sperm as when they were injected with it.Levin says he is exceptionally delighted about the prospective their technique holds, specifically the brief period of time it takes to work in contrast to the approaches that take a number of weeks.

Such a drug, which the authors call an “on-demand” birth control, hasnt been developed.Other male birth control drugs in advancement objective to limit the production of sperm but only end up being efficient after numerous months of taking the drugs, and it takes another 8 to 12-week change period before the individual taking them ends up being fertile again. To make sure it would work as a drug, the scientists partnered with drug business TDI Therapeutics. A working male birth control drug needs to be powerful and “sticky” enough to stick on to the ideal binding website even after entering the female reproductive tract, where the drugs concentration ends up being substantially diluted.