December 1, 2024

New Study: Psychological Issues Like Anxiety and Depression May Play a Role in Long COVID

New UCLA research study suggests that individuals who viewed cognitive problems, such as memory issues during COVID, were more most likely to experience lingering physical symptoms of the illness.
According to new research from UCLA, people who reported experiencing cognitive problems, such as memory problems, during the COVID-19 pandemic are more likely to have persistent physical symptoms of the illness compared to those who did not report such cognitive concerns.
Over a 3rd of individuals fighting with long-term signs of COVID-19 have actually reported cognitive difficulties, including memory issues. These cognitive problems have been linked to increased circumstances of anxiety and depression.
The findings show that mental concerns such as anxiety or depressive disorders might play a part in some people who are experiencing long COVID, technically called post-COVID-19 condition, or PCC.

” This understanding of cognitive deficits suggests that affective problems– in this case stress and anxiety and anxiety– appear to bring over into the long COVID period,” said senior author Dr. Neil Wenger, teacher of medicine in the department of basic internal medication and health services research at the David Geffen School of Medicine at UCLA. “This is not to say that long COVID is all in ones head, but that it is most likely not a single condition and that for some proportion of clients, there is likely a component of stress and anxiety or anxiety that is worsened by the disease.”
The research study was recently published in JAMA Network Open.
Long COVID is referred to as experiencing relentless symptoms of the illness more than 4 weeks after the initial infection. The scientists objective was to identify if there was a link between their patients viewed cognitive difficulties throughout the intense COVID illness and later physical manifestation of long COVID.
The scientists surveyed 766 clients registered in UCLAs SARS-CoV-2 Ambulatory Program who had validated symptomatic COVID infection and had actually either been hospitalized at UCLA or at one of 20 regional healthcare centers or were referred to the program by a primary care physician and been dealt with as outpatients.
Patients were surveyed by telephone at 30 days, 60 days, and 90 days following healthcare facility discharge or, in the case of non-hospitalized clients, after the date of a positive COVID test to ascertain if they felt their health was back to regular. They were asked if they experiencing physical signs of long COVID. For instance, could they finish activities such as running, moving a table, climbing up one flight of stairs, or bring groceries, or did they continue to have a fever, chills, loss of smell, or fatigue?
They were likewise asked 3 questions related to cognitive function: whether they had actually trouble getting arranged or focusing on activities such as viewing television or checking out a book, or had actually forgotten what they discussed in a telephone conversation throughout the previous 4 weeks.
The researchers discovered that 276 (36.1%) of the clients surveyed viewed during the severe health problem or the following weeks that they had cognitive troubles. In addition, these patients were twice as likely as those without perceived cognitive deficits to report also experiencing physical signs at 60 and 90 days.
These include a lack of unbiased cognition steps because the study relied on subjective actions about cognitive deficits. The researchers did not have data on participants possible cognition, anxiety, and stress and anxiety prior to COVID infection.
Still, the findings “may assist us disentangle the complex construct that is PCC,” the scientists compose. “These findings recommend a considerable psychological part for lasting SARS-CoV-2 symptoms for at least some patients.”
Reference: “Perceived Cognitive Deficits in Patients With Symptomatic SARS-CoV-2 and Their Association With Post– COVID-19 Condition” by Teresa C. Liu, MD, MPH, Sun M. Yoo, MD, MPH, Myung S. Sim, DrPH, Yash Motwani, BS, Nisha Viswanathan, MD and Neil S. Wenger, MD, MPH, 5 May 2023, JAMA Network Open.DOI: 10.1001/ jamanetworkopen.2023.11974.
The study was funded by the National Center for Advancing Translational Science of the National Institutes of Health under the UCLA Translational and scientific Science Institute.

Clients were surveyed by telephone at 30 days, 60 days, and 90 days following healthcare facility discharge or, in the case of non-hospitalized clients, after the date of a favorable COVID test to ascertain if they felt their health was back to normal. They were asked if they experiencing physical symptoms of long COVID. These include an absence of objective cognition procedures because the survey relied on subjective reactions about cognitive deficits. The researchers did not have information on participants possible cognition, depression, and anxiety prior to COVID infection.