May 6, 2024

Opinion: Modern Chemistry Is Quite Literally Rubbish

A brand-new paper urges the contemporary chemistry community to focus on ecological sustainability, stressing the requirement for a paradigm shift towards safe, effective, and circular chemistry practices. It promotes for a responsible approach that considers the lifecycle effect of brand-new chemicals on the environment and both humankind.
In a remark in Nature Reviews Chemistry, Ph.D. student Hannah Flerlage and associate professor Chris Slootweg of the University of Amsterdams Vant Hoff Institute for Molecular Sciences argue that modern-day chemists need to widen their horizons and think about the results of chemistry “beyond the reaction vessel and the fume hood.” In order to fight ever-worsening ecological crises, and to attain genuine sustainability, chemistry needs to establish a combined focus on effectiveness, security, and circularity.
Modern chemistry is quite actually rubbish, Flerlage and Slootweg compose, as it helps with the course of matter from extraction to pollution. All sorts of waste, both coming from chemical production procedures and from their typically brief final result, have actually led to human health issue and ecological catastrophes at varying scales.
Undoubtedly, over the previous years a growing number of sustainable synthetic methods have actually become offered, reducing or perhaps removing making use of harmful compounds and waste. However, Flerlage and Slootweg rhetorically ask, is chemistry there yet? Their response: “Not at all!”

Flerlage and Slootweg argue that modern chemistry needs to take such environmental concerns to heart, and right from the start. They even go so far as to consider it dishonest to establish chemistry that will lead to chemical pollution. These three core values of contemporary chemistry are described by the paradigms of green chemistry, safe and sustainable-by-design, and circular chemistry. These need to all be complied with concurrently if chemistry is to make a real contribution to sustainability.
To them, chemistry will just have a favorable and real impact on sustainability when it totally accepts circular style, life-cycle thinking, human and ecological toxicology, and environmental and social impact assessment.

In their view, chemists need to begin looking beyond “cool particles,” and “incredible chemistry.” Sure, it can be fun and rewarding to produce visually pleasing particles. However this overlooks the role of chemistry in the modern world.
As an example, they refer to perfluorocubane, a particle that in 2022 was designated Molecule of the Year. Its synthesis may be a stellar accomplishment, and there will probably be potential future applications. However its structure, including several carbon-fluorine bonds, suggests that perfluorocubane will persist in the environment and bioaccumulate.
The future of chemistry in a nutshell: A triple focus on safety, circularity, and performance is required to steer chemistry towards sustainability. Credit: HIMS
Flerlage and Slootweg argue that contemporary chemistry requires to take such environmental concerns to heart, and right from the start. They even go so far as to consider it unethical to establish chemistry that will cause chemical contamination. They require an end to inadequately developed compounds, in particular “forever chemicals” such as per- and polyfluorinated alkyl compounds and brominated flame retardants.
Systems thinking
As chemistry is the science of the change of matter, not simply of the development of novel particles, Flerlage and Slootweg explain the responsibility to develop safe chemistry and chemicals that utilize the worlds resources most effectively and enhance sustainability.
This requires a method of systems thinking that is grounded in the acknowledgment of sustainability as an emerging residential or commercial property, and directed by an understanding of the molecular basis of sustainability. This means that chemistry should not just focus on minimizing and using eco-friendly resources production waste. It likewise has to consider the life-cycle environmental footprints and total ecological ramifications of (novel) chemicals.
As a slootweg, flerlage and example mention drop-in bio-based polymers such as bioPE, which are made from bioethanol. These polymers lower making use of fossil resources however dont enhance recyclability or biodegradability. And thus they continue to add to plastic pollution.
More challenging, more fulfilling
In their flerlage, slootweg and paper promote a triple concentrate on performance, circularity, and security, both concerning chemical procedures (synthesis) and items (chemical structure). These 3 core values of modern chemistry are described by the paradigms of green chemistry, sustainable-by-design and safe, and circular chemistry. These need to all be abided by all at once if chemistry is to make a genuine contribution to sustainability.
All this will render chemistry more challenging, however also more satisfying, Flerlage and Slootweg compose. “We need to broaden our horizons and consider our chemistry beyond the reaction vessel and the fume hood: how do the materials and particles we make connect with the technosphere (industrial systems and society) and the biosphere (nature)?” To them, chemistry will just have a real and positive effect on sustainability when it completely accepts circular design, life-cycle thinking, human and environmental toxicology, and ecological and social impact evaluation.
Referral: “Modern chemistry is rubbish” by Hannah Flerlage and J. Chris Slootweg, 31 July 2023, Nature Reviews Chemistry.DOI: 10.1038/ s41570-023-00523-9.