May 1, 2024

Decoding Women’s Health: Artificial Intelligence Revolutionizes PCOS Diagnosis

PCOS occurs when the ovaries do not work correctly, and in numerous cases, is accompanied by raised levels of testosterone. Ladies with PCOS are typically at an increased danger for establishing type 2 diabetes, as well as sleep, mental, cardiovascular, and other reproductive disorders such as uterine cancer and infertility.
AI can process enormous quantities of distinct data, such as that obtained from electronic health records, making it an ideal help in the medical diagnosis of difficult-to-diagnose conditions like PCOS.
With the help of a skilled NIH curator, the scientists recognized potentially eligible research studies. All research studies were observational and assessed the use of AI/ML innovations on patient medical diagnosis.

By National Institute of Environmental Health Sciences (NIEHS).
September 26, 2023.

Artificial intelligence (AI) and device knowing (ML) have actually revealed high efficacy in finding and identifying Polycystic Ovary Syndrome (PCOS), a widespread hormonal agent condition in women, according to a research study by the National Institutes of Health.
NIH study evaluates 25 years of data and finds AI/ML can identify common hormone disorder.
Artificial intelligence (AI) and machine learning (ML) can efficiently identify and detect Polycystic Ovary Syndrome (PCOS), which is the most common hormone condition amongst females, normally in between ages 15 and 45, according to a brand-new study by the National Institutes of Health (NIH). Scientist methodically examined published scientific research studies that utilized AI/ML to examine information to identify and classify PCOS and discovered that AI/ML based programs had the ability to effectively detect PCOS.
” Given the large burden of under- and mis-diagnosed PCOS in the community and its possibly serious outcomes, we desired to identify the energy of AI/ML in the identification of patients that may be at risk for PCOS,” said Janet Hall, M.D., senior investigator and endocrinologist at the National Institute of Environmental Health Sciences (NIEHS), part of NIH, and a study co-author. “The effectiveness of AI and machine learning in detecting PCOS was even more outstanding than we had believed.”.

Challenges of Diagnosing PCOS.
PCOS occurs when the ovaries do not work effectively, and in most cases, is accompanied by elevated levels of testosterone. The disorder can trigger irregular durations, acne, extra facial hair, or hair loss from the head. Females with PCOS are typically at an increased risk for developing type 2 diabetes, in addition to sleep, mental, cardiovascular, and other reproductive disorders such as uterine cancer and infertility.
” PCOS can be challenging to diagnose offered its overlap with other conditions,” said Skand Shekhar, M.D., senior author of the research study and assistant research doctor and endocrinologist at the NIEHS. “These information reflect the untapped capacity of incorporating AI/ML in electronic health records and other medical settings to improve the medical diagnosis and care of ladies with PCOS.”.
Study authors recommended integrating big population-based studies with electronic health datasets and examining typical laboratory tests to determine sensitive diagnostic biomarkers that can help with the medical diagnosis of PCOS.
PCOS Diagnostic Criteria and Role of AI/ML.
Medical diagnosis is based upon widely-accepted standardized criteria that have actually progressed throughout the years, but typically consists of clinical functions (e.g., acne, excess hair growth, and irregular periods) accompanied by laboratory (e.g., high blood testosterone) and radiological findings (e.g., several small cysts and increased ovarian volume on ovarian ultrasound). However, due to the fact that a few of the features of PCOS can co-occur with other disorders such as weight problems, diabetes, and cardiometabolic disorders, it often goes unrecognized.
AI describes using computer-based systems or tools to simulate human intelligence and to assist make decisions or forecasts. ML is a neighborhood of AI concentrated on gaining from previous occasions and applying this understanding to future decision-making. AI can process huge quantities of distinct information, such as that obtained from electronic health records, making it a perfect aid in the diagnosis of difficult-to-diagnose conditions like PCOS.
Evaluation Findings.
With the help of a knowledgeable NIH curator, the researchers recognized potentially qualified research studies. In total, they screened 135 studies and consisted of 31 in this paper. All research studies were observational and evaluated the usage of AI/ML technologies on client diagnosis.
Among the 10 research studies that used standardized diagnostic criteria to identify PCOS, the accuracy of detection ranged from 80-90%.
” Across a range of diagnostic and category techniques, there was an extremely high efficiency of AI/ML in spotting PCOS, which is the most crucial takeaway of our study,” stated Shekhar.
The authors keep in mind that AI/ML-based programs have the prospective to substantially boost our capability to determine females with PCOS early, with associated cost savings and a decreased concern of PCOS on clients and on the health system.
Follow-up research studies with robust recognition and testing practices will enable the smooth integration of AI/ML for chronic health conditions.
Reference: “Application of maker knowing and expert system in the diagnosis and classification of polycystic ovarian syndrome: a systematic review” by Francisco J. Barrera, Ethan D.L. Brown, Amanda Rojo, Javier Obeso, Hiram Plata, Eddy P. Lincango, Nancy Terry, René Rodríguez-Gutiérrez, Janet E. Hall and Skand Shekhar, 18 September 2023, Frontiers in Endocrinology.DOI: 10.3389/ fendo.2023.1106625.
This work was supported by the Intramural Research Program of the NIH/National Institute of Environmental Health Sciences (ZIDES102465 and ZIDES103323).