May 15, 2024

The Physical Activity Paradox: New Study Links Physical Labor to Cognitive Impairment

Researchers have actually found that high exercise in the workplace throughout a profession is connected with a greater risk of cognitive disability in old age. Their research advances previous research studies by using a life-course viewpoint, examining occupational activity from ages 33 to 65 and its effect on cognitive health after age 70. The research study, that included over 7,000 individuals, revealed that those in physically requiring jobs had a 15.5% danger of cognitive issues, versus 9% for those in less physically demanding functions. These findings suggest the requirement for interventions to mitigate the threat of dementia in physically demanding professions.
A brand-new research study from the Norwegian National Centre of Ageing and Health, in cooperation with the Columbia Mailman School of Public Health and the Butler Columbia Aging Center, has actually discovered a connection between regularly participating in jobs with moderate to high levels of exercise and a heightened threat of cognitive decline.
These findings highlight the necessity for creating preventive measures for those used in physically demanding occupations to avoid cognitive problems. The findings were recently released in The Lancet Regional Health– Europe.
The Physical Activity Paradox
” It is seriously important to comprehend how workplace physical activity levels connect to cognitive impairment and dementia,” observed Vegard Skirbekk, PhD, professor of Population and Family Health at Columbia Public Health. “Our work likewise highlights what is called the physical activity (PA) paradox– the association of free time physical activity with better cognitive outcomes, and how job-related exercise can lead to worse cognitive outcomes.”

Researchers have actually found that high physical activity in the workplace over the course of a career is associated with a greater threat of cognitive impairment in old age. Their research study advances previous studies by employing a life-course point of view, examining occupational activity from ages 33 to 65 and its effect on cognitive health after age 70. The study, which included over 7,000 individuals, showed that those in physically demanding jobs had a 15.5% threat of cognitive concerns, against 9% for those in less physically demanding functions. Skirbekk and colleagues evaluated the association of trajectories of occupational physical activity at ages 33– 65 with risk of dementia and moderate cognitive problems at ages 70+. “Future research must examine how occupational physical activity and interventions to lower occupational physical activity or technological modifications leading to altered activity, in mix with other qualities of the job, relate to dementia and moderate cognitive impairment threat in older ages.

Approach and Prior Research
Until now prior studies on occupational exercise and dementia had been limited. Earlier research studies have usually assessed occupation at a single time point in the persons profession– frequently near to retirement– and have actually primarily been self-reported.
” Our findings extend those from previous studies by integrating a life-course viewpoint into research study on occupational physical activity and cognitive problems,” said Skirbekk. “Whereas previous research studies have likewise generally concentrated on a single measurement of profession, we include occupational trajectories from ages 33– 65 to give a broader image of the occupational histories of the individuals and how these associate with the risk of cognitive problems in later their adult years.”
Skirbekk observes that the preclinical duration of dementia might launch to 2 years prior to symptom beginning, therefore, a life-course approach where various professions during the working life course are considered might offer more accurate info on the complex relationships between occupational characteristics and cognitive problems.
Research study Findings
Utilizing one of the worlds biggest population-based research studies of dementia, the HUNT4 70+ Study, researchers examined the association of occupational exercise at ages 33– 65 with the risk of dementia and mild cognitive impairment at ages 70+.
Included in the analysis were 7005 participants, 902 whom were medically identified with dementia and 2407 diagnosed with mild cognitive disability. Skirbekk and colleagues evaluated the association of trajectories of occupational physical activity at ages 33– 65 with threat of dementia and mild cognitive problems at ages 70+. Of the 7005 participants, half were women.
Risks for dementia and moderate cognitive impairment amongst the 70-year-old and overpopulation were 15.5 percent amongst those with physically requiring work in the latter part of the working life, however just 9 percent amongst those with tasks that had low physical demands.
” Our outcomes particularly highlight the requirement to follow up on individuals with high lifetime occupational, exercise as they appear to have a greater risk of establishing dementia,” kept in mind Skirbekk. “Future research study ought to examine how occupational exercise and interventions to decrease occupational exercise or technological modifications leading to altered activity, in mix with other attributes of the task, associate with dementia and mild cognitive disability threat in older ages. This will further our understanding of the association between occupational histories and cognitive problems.”
Recommendation: “Trajectories of occupational physical activity and risk of later-life mild cognitive disability and dementia: the HUNT4 70+ research study” by Ekaterina Zotcheva, Bernt Bratsberg, Bjørn Heine Strand, Astanand Jugessur, Bo Lars Engdahl, Catherine Bowen, Geir Selbæk, Hans-Peter Kohler, Jennifer R. Harris, Jordan Weiss, Sarah E. Tom, Steinar Krokstad, Teferi Mekonnen, Trine Holt Edwin, Yaakov Stern, Asta Kristine Håberg and Vegard Skirbekk, 29 August 2023, The Lancet Regional Health– Europe.DOI: 10.1016/ j.lanepe.2023.100721.
Co-author is Ekaterina Zotcheva, Norwegian National Centre of Ageing and Health.
This work was supported by the National Institutes of Health and the Research Council of Norway.