May 2, 2024

Not All Weight Loss Is Good: The Counterintuitive Finding That Could Extend Your Lifespan

The study, just recently published in the Journal of Gerontology: Medical Sciences, examined the relationship between weight fluctuations in later life and durability among 54,437 postmenopausal females getting involved in the Womens Health Initiative. Females who lost at least 5 percent of weight were less most likely to achieve longevity compared to those who achieved stable weight. Females who inadvertently lost weight were 51 percent less most likely to survive to the age of 90. Acquiring 5 percent or more weight, compared to stable weight, was not associated with exceptional durability.

” It is extremely typical for older women in the United States to experience overweight or weight problems with a body mass index series of 25 to 35. Our findings support steady weight as a goal for durability in older females,” stated very first author Aladdin H. Shadyab, Ph.D., M.P.H., associate professor at the Herbert Wertheim School of Public Health and Human Longevity Science at UC San Diego.
” If aging ladies discover themselves losing weight when they are not attempting to drop weight, this might be an indication of disease and a predictor of reduced durability.”
The findings recommend that basic recommendations for weight reduction in older women might not help them live longer. The authors caution that ladies need to hearken medical guidance if moderate weight loss is advised to enhance their health or quality of life.
The data broadens on the growing research connecting the relationship between weight change and mortality. Especially, this is the very first large research study to examine weight change later in life and its relation to remarkable durability.
Recommendation: “Association of Later-Life Weight Changes With Survival to Ages 90, 95, and 100: The Womens Health Initiative” by Aladdin H Shadyab, Ph.D., JoAnn E Manson, MD, DrPH, Matthew A Allison, MD, MPH, Deepika Laddu, Ph.D., Sylvia Wassertheil-Smoller, Ph.D., Linda Van Horn, Ph.D., RDN, Robert A Wild, MD, MPH, Ph.D., Hailey R Banack, Ph.D., Fred K Tabung, Ph.D., Bernhard Haring, MD, MPH, Yangbo Sun, MD, Ph.D., Erin S LeBlanc, MD, MPH, Jean Wactawski-Wende, Ph.D., Meryl S LeBoff, MD, Michelle J Naughton, Ph.D., MPH, Juhua Luo, Ph.D., Peter F Schnatz, DO, Ginny Natale, Ph.D., Robert J Ostfeld, MD, MSc and Andrea Z LaCroix, Ph.D., 29 August 2023, Journal of Gerontology.DOI: 10.1093/ gerona/glad177.
Co-authors include: Matthew A. Allison and Andrea Z. LaCroix, UC San Diego; JoAnn E. Manson, Brigham and Womens Hospital and Harvard Medical School and Harvard T.H. Chan School of Public Health; Deepika Laddu, University of Illinois Chicago; Sylvia Wassertheil-Smoller, Albert Einstein College of Medicine; Linda Van Horn, Northwestern University Feinberg School of Medicine; Robert A. Wild, University of Oklahoma Health Sciences Center; Hailey R. Banack, Dalla Lana School of Public Health; Fred K. Tabung, Ohio State University; Bernhard Haring, University of Wurzburg and Albert Einstein College of Medicine; Yangbo Sun, University of Tennessee Health Science Center; Erin S. LeBlanc, Kaiser Permanente; Jean Wactawski-Wende, University at Buffalo– SUNY; Meryl S. LeBoff, Harvard Medical School; Michelle J. Naughton, Ohio State University; Juhua Luo, Indiana University Bloomington; Peter F. Schnatz, Reading Hospital/Tower Health; Ginny Natale, Stony Brook University; and Robert J. Ostfeld, Montefiore Health System.
This research study was funded, in part, by the National Institutes of Health, National Heart, Lung, and Blood Institute, and U.S. Department of Health and Human Services (75N92021D00001, 75N92021D00002, 75N92021D00003, 75N92021D00004 and 75N92021D00005).
Disclosure: Robert J. Ostfeld, MD, MSc, declares research study grants from Purjes Foundation and Greenbaum Foundation, and is an advisory board member of Mesuron, Inc. with stock alternative interest.

A research study discovered that older women who kept their body weight after age 60 were most likely to reach extraordinary durability compared to those who lost 5% or more of their weight. Gaining weight did not affect the odds of accomplishing remarkable longevity, challenging general suggestions for weight loss in older ladies.
According to a research study led by the University of California San Diego, older females who kept their weight after turning 60 had a greater possibility of living to 90 or beyond, referred to as remarkable durability. These ladies were 1.2 to 2 times more likely to reach this milestone compared to those who lost 5% or more of their body weight.
The research study, just recently published in the Journal of Gerontology: Medical Sciences, evaluated the relationship between weight variations in later life and longevity amongst 54,437 postmenopausal females taking part in the Womens Health Initiative. This long-lasting research study intends to check out the root causes of chronic diseases in postmenopausal females. Throughout the follow-up duration, 30,647 participants, or 56%, lived to the age of 90 or older.
Aladdin H. Shadyab, Ph.D., M.P.H., associate professor at the Herbert Wertheim School of Public Health and Human Longevity Science at UC San Diego Credit: UC San Diego.
Women who lost a minimum of 5 percent of weight were less most likely to accomplish longevity compared to those who attained steady weight. Women who accidentally lost weight were 51 percent less most likely to endure to the age of 90. Gaining 5 percent or more weight, compared to stable weight, was not associated with extraordinary durability.